Publication Name	World Journal of Stem Cells
Manuscript ID	90591
Country	China

Received	2023-12-07 15:54
Peer-Review Started	2023-12-07 15:54
To Make the First Decision
Return for Revision	2024-01-29 21:02
Revised	2024-02-02 05:14
Second Decision	2024-02-29 02:43
Accepted by Journal Editor-in-Chief
Accepted by Company Editor-in-Chief	2024-02-29 06:10
Articles in Press	2024-02-29 06:10
Publication Fee Transferred
Edit the Manuscript by Language Editor
Typeset the Manuscript	2024-03-18 01:13
Publish the Manuscript Online	2024-03-25 02:43

ISSN	1948-0210 (online)
Open Access	This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/Licenses/by-nc/4.0/
Copyright	© The Author(s) 2024. Published by Baishideng Publishing Group Inc. All rights reserved.
Article Reprints	For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
Permissions	For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
Publisher	Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website	http://www.wjgnet.com

Category	Orthopedics
Manuscript Type	Editorial
Article Title	O-linked β-N-acetylglucosaminylation may be a key regulatory factor in promoting osteogenic differentiation of bone marrow mesenchymal stromal cells
Manuscript Source	Invited Manuscript
All Author List	Xu-Chang Zhou and Guo-Xin Ni
ORCID	Author(s) ORCID Number Xu-Chang Zhou http://orcid.org/0000-0003-1390-7659 Guo-Xin Ni http://orcid.org/0000-0001-9181-8155
Funding Agency and Grant Number
Corresponding Author	Guo-Xin Ni, Doctor, MD, PhD, Chief Doctor, Chief Physician, Professor, Department of Rehabilitation Medicine, The First Affiliated Hospital of Xiamen University, No. 55 Zhenhai Road, Siming District, Xiamen 361003, Fujian Province, China. nigx@xmu.edu.cn
Key Words	O-GlcNAcylation; Osteogenic differentiation; Bone marrow mesenchymal stromal cells; Osteoporosis
Core Tip	O-linked β-N-acetylglucosaminylation (O-GlcNAcylation), an important post-translational modification of proteins, widely involved in the regulation of biological processes such as signal transduction and proteasomal degradation, plays an essential role in the initiation and progression of various diseases such as bone metabolism. In this study, we emphasized that maintaining appropriate levels of O-GlcNAcylation is beneficial for the osteogenic differentiation of bone marrow mesenchymal stem cells (BMSCs). Insufficient or excessive levels of O-GlcNAcylation are detrimental to BMSC osteogenic differentiation.
Publish Date	2024-03-25 02:43
Citation	Zhou XC, Ni GX. O-linked β-N-acetylglucosaminylation may be a key regulatory factor in promoting osteogenic differentiation of bone marrow mesenchymal stromal cells. World J Stem Cells 2024; 16(3): 228-231
URL	https://www.wjgnet.com/1948-0210/full/v16/i3/228.htm
DOI	https://dx.doi.org/10.4252/wjsc.v16.i3.228

Full Article (PDF)	WJSC-16-228-with-cover.pdf
Manuscript File	90591_Auto_Edited-YJP.docx
Answering Reviewers	90591-Answering reviewers.pdf
Audio Core Tip	90591-Audio core tip.m4a
Conflict-of-Interest Disclosure Form	90591-Conflict-of-interest statement.pdf
Copyright License Agreement	90591-Copyright license agreement.pdf
Non-Native Speakers of English Editing Certificate	90591-Language certificate.pdf
Peer-review Report	90591-Peer-review(s).pdf
Scientific Misconduct Check	90591-Bing-Wang JJ-2.png
Scientific Editor Work List	90591-Scientific editor work list.pdf