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Articles Published Processes
5/9/2024 1:59:12 PM | Browse: 134 | Download: 804
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Received |
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2023-12-11 02:55 |
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Peer-Review Started |
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2023-12-11 02:55 |
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First Decision by Editorial Office Director |
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2023-12-29 01:15 |
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Return for Revision |
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2023-12-29 01:15 |
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Revised |
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2024-01-09 11:41 |
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Publication Fee Transferred |
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Second Decision by Editor |
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2024-02-19 02:55 |
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Second Decision by Editor-in-Chief |
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Final Decision by Editorial Office Director |
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2024-02-19 06:04 |
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Articles in Press |
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2024-02-19 06:04 |
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Edit the Manuscript by Language Editor |
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Typeset the Manuscript |
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2024-04-24 00:32 |
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Publish the Manuscript Online |
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2024-05-09 13:59 |
| ISSN |
1948-5204 (online) |
| Open Access |
This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/ |
| Copyright |
© The Author(s) 2024. Published by Baishideng Publishing Group Inc. All rights reserved. |
| Article Reprints |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
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| Permissions |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
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| Publisher |
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
| Website |
http://www.wjgnet.com |
| Category |
Gastroenterology & Hepatology |
| Manuscript Type |
Clinical and Translational Research |
| Article Title |
METTL5 promotes gastric cancer progression via sphingomyelin metabolism
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| Manuscript Source |
Unsolicited Manuscript |
| All Author List |
Ya-Qiong Zhang, Jian Li, Zhe Qin, De-Ming Li, Fang-Zhou Ye, Song-Hua Bei, Xiao-Hong Zhang and Li Feng |
| ORCID |
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| Funding Agency and Grant Number |
| Funding Agency |
Grant Number |
| National Natural Science Foundation of China (General Program) |
8217100675 |
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| Corresponding Author |
Xiao-Hong Zhang, Endoscopy Center, Minhang Hospital Affiliated to Fudan University, Shanghai 201100, China. zxh_lp@163.com |
| Key Words |
Cisplatin; Sphingomyelin metabolism; METTL5; Gastric cancer |
| Core Tip |
This study revealed that increased METTL5 expression indicates an unfavorable prognosis and advanced clinical stage in patients with gastric cancer (GC). METTL5 markedly promoted the proliferation, migration, and invasion of GC cells. METTL5 stimulated the metabolism of sphingomyelin to induce GC tumorigenesis. In addition, METTL5 weakened the sensitivity of GC cells to cisplatin, serving as a novel target for GC treatment. |
| Publish Date |
2024-05-09 13:59 |
| Citation |
Zhang YQ, Li J, Qin Z, Li DM, Ye FZ, Bei SH, Zhang XH, Feng L. METTL5 promotes gastric cancer progression via sphingomyelin metabolism. World J Gastrointest Oncol 2024; 16(4): 1925-1946 |
| URL |
https://www.wjgnet.com/1948-5204/full/v16/i5/1925.htm |
| DOI |
https://dx.doi.org/10.4251/wjgo.v16.i5.1925 |
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