Publication Name	World Journal of Hepatology
Manuscript ID	90711
Country	Thailand

Received	2023-12-12 06:20
Peer-Review Started	2023-12-12 06:20
To Make the First Decision
Return for Revision	2024-01-27 13:50
Revised	2024-02-03 11:22
Second Decision	2024-03-12 02:45
Accepted by Journal Editor-in-Chief
Accepted by Executive Editor-in-Chief	2024-03-12 06:01
Articles in Press	2024-03-12 06:01
Publication Fee Transferred
Edit the Manuscript by Language Editor
Typeset the Manuscript	2024-04-09 07:14
Publish the Manuscript Online	2024-04-24 08:35

ISSN	1948-5182 (online)
Open Access	This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/Licenses/by-nc/4.0/
Copyright	© The Author(s) 2024. Published by Baishideng Publishing Group Inc. All rights reserved.
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Category	Gastroenterology & Hepatology
Manuscript Type	Review
Article Title	Quantitative hepatitis B core antibody and quantitative hepatitis B surface antigen: Novel viral biomarkers for chronic hepatitis B management
Manuscript Source	Invited Manuscript
All Author List	Wattana Leowattana, Pathomthep Leowattana and Tawithep Leowattana
ORCID	Author(s) ORCID Number Wattana Leowattana http://orcid.org/0000-0003-4257-2480 Tawithep Leowattana http://orcid.org/0000-0003-2316-3585
Funding Agency and Grant Number
Corresponding Author	Wattana Leowattana, MD, PhD, Full Professor, Department of Clinical Tropical Medicine, Mahidol University, 420/6 Rajavithi Road, Rachatawee 10400, Bangkok, Thailand. wattana.leo@mahidol.ac.th
Key Words	Quantitative hepatitis B core antibody; Quantitative hepatitis B surface antigen; Chronic hepatitis B management; Novels viral biomarkers
Core Tip	It is possible to employ a quantitative hepatitis B virus (HBV) core antibody (qAnti-HBc) level as a predictor of therapeutic response, recurrence after hepatitis B surface antigen (HBsAg) loss, and HBsAg seroclearance. Just like other newly identified biomarkers, qAnti-HBc is not a stand-alone diagnostic test that can solve every issue. The information that is now available indicates that it may have a much higher diagnostic and prognostic effectiveness when combined with quantitative HBsAg. Further research involving larger and more variable patients is required to assess the actual usefulness of these biomarkers.
Publish Date	2024-04-24 08:35
Citation	Leowattana W, Leowattana P, Leowattana T. Quantitative hepatitis B core antibody and quantitative hepatitis B surface antigen: Novel viral biomarkers for chronic hepatitis B management. World J Hepatol 2024; 16(4): 550-565
URL	https://www.wjgnet.com/1948-5182/full/v16/i4/550.htm
DOI	https://dx.doi.org/10.4254/wjh.v16.i4.550

Full Article (PDF)	WJH-16-550-with-cover.pdf
Manuscript File	90711_Auto_Edited-YJP.docx
Answering Reviewers	90711-Answering reviewers.pdf
Audio Core Tip	90711-Audio core tip.m4a
Conflict-of-Interest Disclosure Form	90711-Conflict-of-interest statement.pdf
Copyright License Agreement	90711-Copyright license agreement.pdf
Non-Native Speakers of English Editing Certificate	90711-Language certificate.pdf
Peer-review Report	90711-Peer-review(s).pdf
Scientific Misconduct Check	90711-CrossCheck.jpg
Scientific Misconduct Check	90711-Bing-Gong ZM-2.png
Scientific Editor Work List	90711-Scientific editor work list.pdf
CrossCheck Report	90711-CrossCheck report.pdf