Publication Name	World Journal of Clinical Pediatrics
Manuscript ID	90755
Country	Saudi Arabia

Received	2023-12-12 17:59
Peer-Review Started	2023-12-12 17:59
To Make the First Decision
Return for Revision	2023-12-19 06:26
Revised	2024-01-01 08:01
Second Decision	2024-02-06 02:38
Accepted by Journal Editor-in-Chief
Accepted by Executive Editor-in-Chief	2024-02-06 10:54
Articles in Press	2024-02-06 10:54
Publication Fee Transferred
Edit the Manuscript by Language Editor
Typeset the Manuscript	2024-02-29 00:39
Publish the Manuscript Online	2024-03-07 02:39

ISSN	2219-2808 (online)
Open Access	This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
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Category	Gastroenterology & Hepatology
Manuscript Type	Observational Study
Article Title	Gut microbiota predicts the diagnosis of ulcerative colitis in Saudi children
Manuscript Source	Invited Manuscript
All Author List	Mohammad El Mouzan, Ahmed Al Sarkhy and Asaad Assiri
ORCID	Author(s) ORCID Number Mohammad El Mouzan http://orcid.org/0000-0001-8699-3143 Ahmed Al Sarkhy http://orcid.org/0000-0002-1424-5784 Asaad Assiri http://orcid.org/0000-0003-3357-5794
Funding Agency and Grant Number
Corresponding Author	Mohammad El Mouzan, MD, Full Professor, Department of Pediatrics, Gastroenterology Unit, King Saud University, 1, King Abdullah Street, Riyadh 11461, Saudi Arabia. melmouzan@ksu.edu.sa
Key Words	Ulcerative colitis; Microbiota; Area under the curve; Children; Saudi Arabia
Core Tip	This study reports the predictive power of fecal microbiota, bacteria and bacteriophages, in predicting the diagnosis of ulcerative colitis in children. This was demonstrated by the calculation of the area under the receiver operating characteristic curve (AUC). High values of the AUC up to 97.6% and 94.5% for bacteria and bacteriophage, respectively, indicate excellent predictive power in differentiating children with ulcerative colitis (UC) from controls. This finding may lead to the development of noninvasive microbiota-based test for the diagnosis of unusual cases of UC in children.
Publish Date	2024-03-07 02:39
Citation	El Mouzan M, Al Sarkhy A, Assiri A. Gut microbiota predicts the diagnosis of ulcerative colitis in Saudi children. World J Clin Pediatr 2024; 13(1): 90755
URL	https://www.wjgnet.com/2219-2808/full/v13/i1/90755.htm
DOI	https://dx.doi.org/10.5409/wjcp.v13.i1.90755

Full Article (PDF)	WJCP-13-90755-with-cover.pdf
Full Article (Word)	90755.docx
STROBE Statement	90755-STROBE statement.pdf
Manuscript File	90755_Auto_Edited-LJH-YJP.docx
Answering Reviewers	90755-Answering reviewers.pdf
Audio Core Tip	90755-Audio core tip.mp3
Biostatistics Review Certificate	90755-Biostatistics statement.pdf
Conflict-of-Interest Disclosure Form	90755-Conflict-of-interest statement.pdf
Copyright License Agreement	90755-Copyright license agreement.pdf
Approved Grant Application Form(s) or Funding Agency Copy of any Approval Document(s)	90755-Grant application form(s).pdf
Signed Informed Consent Form(s) or Document(s)	90755-Informed consent statement.pdf
Institutional Review Board Approval Form or Document	90755-Institutional review board statement.pdf
Non-Native Speakers of English Editing Certificate	90755-Language certificate.pdf
Peer-review Report	90755-Peer-review(s).pdf
Scientific Misconduct Check	90755-Bing-Liu JH-2.png
Scientific Misconduct Check	90755-CrossCheck.png
Scientific Editor Work List	90755-Scientific editor work list.pdf
CrossCheck Report	90755-CrossCheck report.pdf