Publication Name	World Journal of Diabetes
Manuscript ID	90787
Country	Croatia

Received	2023-12-13 11:56
Peer-Review Started	2023-12-13 11:56
To Make the First Decision
Return for Revision	2024-01-24 05:52
Revised	2024-02-04 21:09
Second Decision	2024-03-24 07:09
Accepted by Journal Editor-in-Chief
Accepted by Executive Editor-in-Chief	2024-04-01 05:34
Articles in Press	2024-04-01 05:34
Publication Fee Transferred
Edit the Manuscript by Language Editor
Typeset the Manuscript	2024-04-26 00:30
Publish the Manuscript Online	2024-05-10 11:51

ISSN	1948-9358 (online)
Open Access	This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/
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Category	Endocrinology & Metabolism
Manuscript Type	Minireviews
Article Title	Challenges and pitfalls of youth-onset type 2 diabetes
Manuscript Source	Invited Manuscript
All Author List	Lavinia La Grasta Sabolic, Sanda Marusic and Maja Cigrovski Berkovic
ORCID	Author(s) ORCID Number Lavinia La Grasta Sabolic http://orcid.org/0000-0001-9114-7961 Sanda Marusic http://orcid.org/0009-0008-3836-2345 Maja Cigrovski Berkovic http://orcid.org/0000-0003-0750-9785
Funding Agency and Grant Number
Corresponding Author	Maja Cigrovski Berkovic, MD, PhD, Associate Professor, Department for Sport and Exercise Medicine, University of Zagreb Faculty of Kinesiology, Horvacanski Zavoj 15, Zagreb 10000, Croatia. maja.cigrovskiberkovic@gmail.com
Key Words	Youth-onset type 2 diabetes mellitus; Insulin resistance; Beta cell failure; Risk factors; Therapy; Complications
Core Tip	Youth-onset type 2 diabetes mellitus (T2DM) is a growing medical challenge, affecting children and adolescents worldwide. Its clinical course is often more aggressive than in type 1 or adult-onset type 2 diabetes, with earlier development of complications. Results of lifestyle interventions have been disappointing, yet the available pharmacotherapy options for children and adolescents with T2DM are still more limited than for adult patients. The introduction of newer agents that target glycemic control, but also promote weight loss and offer cardiovascular and renal benefits, has the potential to significantly improve the health trajectory of youth with T2DM.
Publish Date	2024-05-10 11:51
Citation	La Grasta Sabolic L, Marusic S, Cigrovski Berkovic M. Challenges and pitfalls of youth-onset type 2 diabetes. World J Diabetes 2024; 15(5): 876-885
URL	https://www.wjgnet.com/1948-9358/full/v15/i5/876.htm
DOI	10.4239/wjd.v15.i5.876

Full Article (PDF)	WJD-15-876-with-cover.pdf
Full Article (Word)	WJD-15-876.docx
Manuscript File	90787_Auto_Edited-YJP.docx
Answering Reviewers	90787-Answering reviewers.pdf
Audio Core Tip	90787-Audio core tip.wav
Conflict-of-Interest Disclosure Form	90787-Conflict-of-interest statement.pdf
Copyright License Agreement	90787-Copyright license agreement.pdf
Non-Native Speakers of English Editing Certificate	90787-Language certificate.pdf
Peer-review Report	90787-Peer-review(s).pdf
Journal Editor-in-Chief Review Report	90787-Journal editor-in-chief review report.pdf
Scientific Misconduct Check	90787-Bing-Li L-2.png
Scientific Editor Work List	90787-Scientific editor work list.pdf
CrossCheck Report	90787-CrossCheck.png
CrossCheck Report	90787-CrossCheck report.pdf