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4/11/2024 2:23:39 AM | Browse: 10 | Download: 40
Publication Name World Journal of Gastrointestinal Oncology
Manuscript ID 90819
Country China
Received
2023-12-14 09:25
Peer-Review Started
2023-12-14 09:25
To Make the First Decision
Return for Revision
2024-01-06 04:03
Revised
2024-01-10 08:40
Second Decision
2024-03-04 02:52
Accepted by Journal Editor-in-Chief
Accepted by Company Editor-in-Chief
2024-03-04 05:39
Articles in Press
2024-03-04 05:39
Publication Fee Transferred
Edit the Manuscript by Language Editor
2024-03-01 12:49
Typeset the Manuscript
2024-03-19 02:54
Publish the Manuscript Online
2024-04-11 02:23
ISSN 1948-5204 (online)
Open Access This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/Licenses/by-nc/4.0/
Copyright © The Author(s) 2024. Published by Baishideng Publishing Group Inc. All rights reserved.
Article Reprints For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
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Publisher Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website http://www.wjgnet.com
Category Medicine, General & Internal
Manuscript Type Retrospective Study
Article Title Prognostic analysis of related factors of adverse reactions to immunotherapy in advanced gastric cancer and establishment of a nomogram model
Manuscript Source Unsolicited Manuscript
All Author List Xu-Xu He, Bang Du, Tao Wu and Hao Shen
ORCID
Author(s) ORCID Number
Xu-Xu He http://orcid.org/0009-0007-6616-1842
Funding Agency and Grant Number
Corresponding Author Xu-Xu He, PhD, Assistant Professor, Department of Surgery, Fudan University Affiliated Zhongshan Hospital (Qingpu Branch), No. 1158 Xiayang Street Park East Road, Qingpu District, Shanghai 201700, China. xuxu19930318@126.com
Key Words Advanced gastric cancer; Prognostic analysis; Immunotherapy; Nomogram model
Core Tip To explore the characteristics and predictors of immune-related adverse reactions (irAEs) in advanced gastric cancer patients receiving immunotherapy with programmed death protein-1 (PD-1) inhibitors, and to analyze the correlation between irAEs and patient prognosis. A total of 132 patients were followed up, of whom 63 (47.7%) developed irAEs. The clinical characteristics of the two groups were compared, and there were statistically significant differences in age ≥ 65 years, Ki-67 index, white blood cell count, neutrophil count, and regulatory T cell (Treg) count between the two groups (all P < 0.05). Multivariate logistic regression analysis showed that Treg count was a protective factor affecting irAEs occurrence (P = 0.030).
Publish Date 2024-04-11 02:23
Citation He XX, Du B, Wu T, Shen H. Prognostic analysis of related factors of adverse reactions to immunotherapy in advanced gastric cancer and establishment of a nomogram model. World J Gastrointest Oncol 2024; 16(4): 1268-1280
URL https://www.wjgnet.com/1948-5204/full/v16/i4/1268.htm
DOI https://dx.doi.org/10.4251/wjgo.v16.i4.1268
Full Article (PDF) WJGO-16-1268-with-cover.pdf
Manuscript File 90819_Auto_Edited-JJW-Webster J-YJP.docx
Answering Reviewers 90819-Answering reviewers.pdf
Audio Core Tip 90819-Audio core tip.mp3
Biostatistics Review Certificate 90819-Biostatistics statement.pdf
Conflict-of-Interest Disclosure Form 90819-Conflict-of-interest statement.pdf
Copyright License Agreement 90819-Copyright license agreement.pdf
Signed Informed Consent Form(s) or Document(s) 90819-Informed consent statement.pdf
Institutional Review Board Approval Form or Document 90819-Institutional review board statement.pdf
Non-Native Speakers of English Editing Certificate 90819-Language certificate.pdf
Peer-review Report 90819-Peer-review(s).pdf
Scientific Misconduct Check 90819-Bing-Wang JJ-2.png
Scientific Editor Work List 90819-Scientific editor work list.pdf
CrossCheck Report 90819-CrossCheck report.pdf