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Articles Published Processes
7/12/2024 3:55:58 PM | Browse: 68 | Download: 251
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Received |
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2023-12-15 02:58 |
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Peer-Review Started |
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2023-12-15 02:58 |
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To Make the First Decision |
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Return for Revision |
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2024-03-30 05:34 |
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Revised |
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2024-04-25 09:38 |
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Second Decision |
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2024-05-17 02:44 |
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Accepted by Journal Editor-in-Chief |
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Accepted by Executive Editor-in-Chief |
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2024-05-17 06:31 |
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Articles in Press |
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2024-05-17 06:31 |
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Publication Fee Transferred |
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Edit the Manuscript by Language Editor |
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Typeset the Manuscript |
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2024-05-28 01:10 |
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Publish the Manuscript Online |
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2024-07-12 15:55 |
| ISSN |
1948-5204 (online) |
| Open Access |
This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/ |
| Copyright |
© The Author(s) 2024. Published by Baishideng Publishing Group Inc. All rights reserved. |
| Article Reprints |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
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| Permissions |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
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| Publisher |
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
| Website |
http://www.wjgnet.com |
| Category |
Gastroenterology & Hepatology |
| Manuscript Type |
Basic Study |
| Article Title |
Yiqi Jiedu Huayu decoction inhibits precancerous lesions of chronic atrophic gastritis by inhibiting NLRP3 inflammasome-mediated pyroptosis
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| Manuscript Source |
Unsolicited Manuscript |
| All Author List |
Peng Zhou, Zi-Han Zheng, Tao Wan, Chuan-Wen Liao and Jie Wu |
| ORCID |
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| Funding Agency and Grant Number |
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| Corresponding Author |
Jie Wu, MBBS, Chief Nurse, Department of Gastrointestinal Surgery, Jiangxi Provincial People's Hospital, The First Affiliated Hospital of Nanchang Medical College, No. 152 Aiguo Road, Donghu District, Nanchang 330006, Jiangxi Province, China. jj18jiewu@sina.com |
| Key Words |
Chronic atrophic gastritis; Yiqi Jiedu Huayu decoction; NLRP3; Pyroptosis |
| Core Tip |
Yiqi Jiedu Huayu decoction (YJHD), an empirical formula comprising multiple traditional Chinese medicines, has demonstrated efficacy in preventing and treatment of human gastrointestinal tumors. However, its impact on precancerous lesion of gastric cancer (PLGC) remains poorly understood, making this study significant. Here, we found that YJHD treatment markedly inhibited PLGC. Additionally, our experiments indicated that YJHD inhibited NLRP3 inflammasome formation and pyroptosis of epithelial cells in chronic atrophic gastritis by deactivating the TLR4/NF-κB and IL-6/STAT3 pathways. |
| Publish Date |
2024-07-12 15:55 |
| Citation |
<p>Zhou P, Zheng ZH, Wan T, Liao CW, Wu J. Yiqi Jiedu Huayu decoction inhibits precancerous lesions of chronic atrophic gastritis by inhibiting NLRP3 inflammasome-mediated pyroptosis. <i>World J Gastrointest Oncol</i> 2024; 16(7): 3158-3168</p> |
| URL |
https://www.wjgnet.com/1948-5204/full/v16/i7/3158.htm |
| DOI |
https://dx.doi.org/10.4251/wjgo.v16.i7.3158 |
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