| ISSN |
1948-0210 (online) |
| Open Access |
This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/Licenses/by-nc/4.0/ |
| Copyright |
© The Author(s) 2024. Published by Baishideng Publishing Group Inc. All rights reserved. |
| Article Reprints |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
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| Permissions |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
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| Publisher |
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
| Website |
http://www.wjgnet.com |
| Category |
Cell & Tissue Engineering |
| Manuscript Type |
Basic Study |
| Article Title |
Therapeutic potential of urine-derived stem cells in renal regeneration following acute kidney injury: A comparative analysis with mesenchymal stem cells
|
| Manuscript Source |
Unsolicited Manuscript |
| All Author List |
Fang Li, Bin Zhao, Lei Zhang, Guo-Qing Chen, Li Zhu, Xiao-Ling Feng, Meng-Jia Gong, Cheng-Chen Hu, Yuan-Yuan Zhang, Ming Li and Yong-Qiang Liu |
| ORCID |
|
| Funding Agency and Grant Number |
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| Corresponding Author |
Yong-Qiang Liu, MD, PhD, Assistant Professor, Department of General Surgery, Chongqing General Hospital, No. 118 Xingguang Avenue, Liangjiang New District, Chongqing 401147, China. wklyq007@163.com |
| Key Words |
Urine-derived stem cells; Regenerative medicine; Acute kidney injury; Renal function recovery; Cell therapy |
| Core Tip |
This study reveals that urine-derived stem cells (USCs) significantly enhance renal function and histological recovery in severe combined immune deficiency mice with glycerol-induced acute kidney injury (AKI). By comparing USCs with bone marrow-derived mesenchymal stem cells, the research highlights USCs’ potential as a novel, non-invasive cell source for AKI treatment. The findings suggest that USCs, through their multidifferentiation potential and secretion of various cytokines and growth factors, offer a promising therapeutic strategy for AKI, potentially altering clinical approaches to renal repair. |
| Publish Date |
2024-05-24 08:33 |
| Citation |
Li F, Zhao B, Zhang L, Chen GQ, Zhu L, Feng XL, Gong MJ, Hu CC, Zhang YY, Li M, Liu YQ. Therapeutic potential of urine-derived stem cells in renal regeneration following acute kidney injury: A comparative analysis with mesenchymal stem cells. World J Stem Cells 2024; 16(5): 525-537 |
| URL |
https://www.wjgnet.com/1948-0210/full/v16/i5/525.htm |
| DOI |
https://dx.doi.org/10.4252/wjsc.v16.i5.525 |
