Publication Name	World Journal of Gastroenterology
Manuscript ID	91035
Country	China

Received	2024-01-25 05:02
Peer-Review Started	2024-01-25 05:02
To Make the First Decision
Return for Revision	2024-02-08 08:40
Revised	2024-02-18 04:55
Second Decision	2024-03-22 02:43
Accepted by Journal Editor-in-Chief
Accepted by Executive Editor-in-Chief	2024-03-22 05:39
Articles in Press	2024-03-22 05:39
Publication Fee Transferred
Edit the Manuscript by Language Editor
Typeset the Manuscript	2024-04-21 07:12
Publish the Manuscript Online	2024-04-26 08:53

ISSN	1007-9327 (print) and 2219-2840 (online)
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Category	Gastroenterology & Hepatology
Manuscript Type	Observational Study
Article Title	Association between childhood obesity and gut microbiota: 16S rRNA gene sequencing-based cohort study
Manuscript Source	Unsolicited Manuscript
All Author List	Xu-Ming Li, Qing Lv, Ya-Jun Chen, Lu-Biao Yan and Xin Xiong
ORCID	Author(s) ORCID Number Xu-Ming Li http://orcid.org/0009-0008-3141-1079 Qing Lv http://orcid.org/0009-0000-8109-4253 Xin Xiong http://orcid.org/0009-0001-0863-6105
Funding Agency and Grant Number
Corresponding Author	Xin Xiong, MSc, Attending Doctor, Department of Neonatology, Chenzhou First People’s Hospital, No. 6 Feihong Road, Chenzhou 423000, Hunan Province, China. dxtw306@163.com
Key Words	Childhood obesity; Gut microbiota; 16S rDNA sequencing; Diversity analysis; Genus identification; Body mass index
Core Tip	This study used 16S rDNA sequencing to identify characteristic gut genera in obese and normal-weight children. The findings revealed lower α-diversity in the gut microbiota of obese children compared to normal-weight children. Significant differences were observed in the composition of gut microbiota between the two groups, with Prevotella and Firmicutes being more abundant in the obese group, and Bacteroides and Sanguibacteroides more prevalent in the control group. These results provide insights into the potential role of gut microbiota in childhood obesity and may contribute to future mechanistic studies and prevention strategies.
Publish Date	2024-04-26 08:53
Citation	Li XM, Lv Q, Chen YJ, Yan LB, Xiong X. Association between childhood obesity and gut microbiota: 16S rRNA gene sequencing-based cohort study. World J Gastroenterol 2024; 30(16): 2249-2257
URL	https://www.wjgnet.com/1007-9327/full/v30/i16/2249.htm
DOI	https://dx.doi.org/10.3748/wjg.v30.i16.2249

Full Article (PDF)	WJG-30-2249-with-cover.pdf
STROBE Statement	91035-STROBE statement.pdf
Manuscript File	91035_Auto_Edited-YJP.docx
Answering Reviewers	91035-Answering reviewers.pdf
Audio Core Tip	91035-Audio core tip.mp3
Biostatistics Review Certificate	91035-Biostatistics statement.pdf
Conflict-of-Interest Disclosure Form	91035-Conflict-of-interest statement.pdf
Copyright License Agreement	91035-Copyright license agreement.pdf
Signed Informed Consent Form(s) or Document(s)	91035-Informed consent statement.pdf
Institutional Review Board Approval Form or Document	91035-Institutional review board statement.pdf
Non-Native Speakers of English Editing Certificate	91035-Language certificate.pdf
Peer-review Report	91035-Peer-review(s).pdf
Scientific Misconduct Check	91035-Bing-Chen YL-2.png
Scientific Editor Work List	91035-Scientific editor work list.pdf
CrossCheck Report	91035-CrossCheck report.pdf