ISSN |
2220-3230 (online) |
Open Access |
This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/ |
Copyright |
© The Author(s) 2024. Published by Baishideng Publishing Group Inc. All rights reserved. |
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Publisher |
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
Website |
http://www.wjgnet.com |
Category |
Medicine, General & Internal |
Manuscript Type |
Editorial |
Article Title |
Tacrolimus-induced posterior reversible encephalopathy syndrome following liver transplantation
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Manuscript Source |
Invited Manuscript |
All Author List |
Arthur Dilibe, Lakshmi Subramanian, Tracy-Ann Poyser, Osejie Oriaifo, Ryan Brady, Sashwath Srikanth, Olanrewaju Adabale, Olayiwola Akeem Bolaji and Hassam Ali |
ORCID |
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Funding Agency and Grant Number |
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Corresponding Author |
Hassam Ali, MD, Doctor, Doctor, Division of Gastroenterology and Hepatology, East Carolina University/Brody School of Medicine, 2100 Statonsburg Road, Greenville, Greenville, NC 27858, United States. hassamali155@gmail.com |
Key Words |
Posterior reversible encephalopathy syndrome; Liver transplantation; Tacrolimus; Immunocompromised patients; Neurological complications; Solid organ transplant |
Core Tip |
Tacrolimus, a crucial immunosuppressant in liver transplantation, is associated with the rare but serious complication of posterior reversible encephalopathy syndrome (PRES). Although the incidence is relatively low (0.5%-5%) in solid organ transplant recipients, the presentation of PRES can vary significantly, including seizures and visual disturbances. This condition, primarily affecting the parietal and occipital lobes, underscores the need for diligent monitoring and early intervention in liver transplant patients undergoing Tacrolimus therapy. The case presented highlights the complexities in diagnosing and managing Tacrolimus-related PRES, emphasizing the critical balance between adequate immunosuppression and the risk of severe neurological adverse effects. |
Publish Date |
2024-06-14 08:01 |
Citation |
<p>Dilibe A, Subramanian L, Poyser TA, Oriaifo O, Brady R, Srikanth S, Adabale O, Bolaji OA, Ali H. Tacrolimus-induced posterior reversible encephalopathy syndrome following liver transplantation. <i>World J Transplant</i> 2024; 14(2): 91146</p> |
URL |
https://www.wjgnet.com/2220-3230/full/v14/i2/91146.htm |
DOI |
https://dx.doi.org/10.5500/wjt.v14.i2.91146 |