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10/16/2024 10:39:00 AM | Browse: 350 | Download: 1273
Publication Name World Journal of Diabetes
Manuscript ID 91297
Country China
Received
2023-12-26 13:33
Peer-Review Started
2023-12-26 13:33
First Decision by Editorial Office Director
2024-05-25 02:28
Return for Revision
2024-05-25 02:28
Revised
2024-06-10 03:46
Publication Fee Transferred
2024-09-13 14:04
Second Decision by Editor
2024-07-08 08:59
Second Decision by Editor-in-Chief
Final Decision by Editorial Office Director
2024-09-10 07:40
Articles in Press
2024-09-10 07:40
Edit the Manuscript by Language Editor
2024-09-18 08:59
Typeset the Manuscript
2024-09-27 05:58
Publish the Manuscript Online
2024-10-16 10:39
ISSN 1948-9358 (online)
Open Access This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/licenses/by-nc/4.0/
Copyright © The Author(s) 2024. Published by Baishideng Publishing Group Inc. All rights reserved.
Article Reprints For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
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Publisher Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website http://www.wjgnet.com
Category Endocrinology & Metabolism
Manuscript Type Review
Article Title Autophagy-dependent ferroptosis may play a critical role in early stages of diabetic retinopathy
Manuscript Source Unsolicited Manuscript
All Author List Wen-Jie Sun, Xue-Dong An, Yue-Hong Zhang, Shan-Shan Tang, Yu-Ting Sun, Xiao-Min Kang, Lin-Lin Jiang, Xue-Fei Zhao, Qing Gao, Hang-Yu Ji and Feng-Mei Lian
ORCID
Author(s) ORCID Number
Wen-Jie Sun http://orcid.org/0009-0009-0861-2443
Feng-Mei Lian http://orcid.org/0000-0003-2222-7487
Funding Agency and Grant Number
Funding Agency Grant Number
the National Natural Science Foundation of China 82305205
the clinical research business fund of the Central High-level Traditional Chinese Medicine Hospital HLCMHPP2023084
Chinese Association of Traditional Chinese Medicine (2023-2025) Youth Talent Support Project CACM-2023-QNRC2-A05
Corresponding Author Feng-Mei Lian, PhD, Professor, Department of Endocrinology, Guang’anmen Hospital, No. 5 Beixiange, Xicheng District, Beijing 100053, China. lfm565@sohu.com
Key Words Diabetic retinopathy; Diabetes mellitus; Retinal neurovascular unit; Autophagy-dependent ferroptosis; Early stage; Mechanisms
Core Tip This article initially investigates the early pathological alterations of diabetic retinopathy (DR), with a particular emphasis on the retinal neurovascular unit (NVU) as a pivotal focal point in the initial stage of DR. Recent studies have revealed that ferroptosis may exert a significant role in the early phase of DR. Autophagy-dependent ferroptosis -related factors, including BECN1 and FABP4, could potentially serve as biomarkers for the onset and progression of DR, thereby representing promising targets for effective treatment strategies in the future. These findings provide novel insights into understanding the mechanisms underlying early pathological changes in DR and offer supplementary avenues for innovative research on treatment approaches.
Publish Date 2024-10-16 10:39
Citation

Sun WJ, An XD, Zhang YH, Tang SS, Sun YT, Kang XM, Jiang LL, Zhao XF, Gao Q, Ji HY, Lian FM. Autophagy-dependent ferroptosis may play a critical role in early stages of diabetic retinopathy. World J Diabetes 2024; 15(11): 2189-2202

URL https://www.wjgnet.com/1948-9358/full/v15/i11/2189.htm
DOI https://dx.doi.org/10.4239/wjd.v15.i11.2189
Full Article (PDF) WJD-15-2189-with-cover.pdf