BPG is committed to discovery and dissemination of knowledge
Articles Published Processes
5/9/2024 1:59:12 PM | Browse: 105 | Download: 555
 |
Received |
|
2023-12-27 03:28 |
|
Peer-Review Started |
|
2023-12-27 03:28 |
|
First Decision by Editorial Office Director |
|
2024-01-16 05:45 |
|
Return for Revision |
|
2024-01-16 05:45 |
|
Revised |
|
2024-01-30 05:14 |
 |
Publication Fee Transferred |
|
|
|
Second Decision by Editor |
|
2024-03-11 02:43 |
|
Second Decision by Editor-in-Chief |
|
|
|
Final Decision by Editorial Office Director |
|
2024-03-11 05:05 |
|
Articles in Press |
|
2024-03-11 05:05 |
|
Edit the Manuscript by Language Editor |
|
|
|
Typeset the Manuscript |
|
2024-04-23 08:19 |
|
Publish the Manuscript Online |
|
2024-05-09 13:59 |
| ISSN |
1948-5204 (online) |
| Open Access |
This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/ |
| Copyright |
© The Author(s) 2024. Published by Baishideng Publishing Group Inc. All rights reserved. |
| Article Reprints |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
|
| Permissions |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
|
| Publisher |
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
| Website |
http://www.wjgnet.com |
| Category |
Immunology |
| Manuscript Type |
Review |
| Article Title |
Mechanisms of myeloid-derived suppressor cell-mediated immunosuppression in colorectal cancer and related therapies
|
| Manuscript Source |
Invited Manuscript |
| All Author List |
Shu-Chang Nie, Yan-Hua Jing, Lu Lu, Si-Si Ren, Guang Ji and Han-Chen Xu |
| ORCID |
|
| Funding Agency and Grant Number |
| Funding Agency |
Grant Number |
| National Natural Science Foundation of China |
No. 82320108022, No. 82322076 and No. 82104466 |
|
| Corresponding Author |
Han-Chen Xu, MD, PhD, Doctor, Doctor, Institute of Digestive Diseases, Longhua Hospital, China-Canada Center of Research for Digestive Diseases, Shanghai University of Traditional Chinese Medicine, No. 725 South Wanping Road, Xuhui District, Shanghai 200032, China. hanson0702@126.com |
| Key Words |
Immunosuppression; Therapy; Colorectal cancer; Tumor microenvironment; Myeloid-derived suppressor cells |
| Core Tip |
Severe immunosuppression is a hallmark of colorectal cancer (CRC). Myeloid-derived suppressor cells (MDSCs), one of the most abundant components of the tumor stroma, play an important role in the invasion, metastasis, and immune escape of CRC. In this study, we focused on the mechanisms through which MDSCs contribute to the immunosuppressive microenvironment, current therapeutic approaches and technologies targeting MDSCs, and the therapeutic potential of modulating MDSCs in CRC treatment. This study provides ideas and methods to enhance survival rates in patients with CRC. |
| Publish Date |
2024-05-09 13:59 |
| Citation |
Nie SC, Jing YH, Lu L, Ren SS, Ji G, Xu HC. Mechanisms of myeloid-derived suppressor cell-mediated immunosuppression in colorectal cancer and related therapies. World J Gastrointest Oncol 2024; 16(5): 1690-1704 |
| URL |
https://www.wjgnet.com/1948-5204/full/v16/i5/1690.htm |
| DOI |
10.4251/wjgo.v16.i5.1690 |
© 2004-2026 Baishideng Publishing Group Inc. All rights reserved. 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
California Corporate Number: 3537345
