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Articles Published Processes
5/9/2024 1:59:12 PM | Browse: 109 | Download: 292
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Received |
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2023-12-27 17:20 |
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Peer-Review Started |
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2023-12-27 17:20 |
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To Make the First Decision |
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Return for Revision |
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2024-02-05 06:03 |
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Revised |
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2024-02-17 17:22 |
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Second Decision |
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2024-03-19 02:46 |
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Accepted by Journal Editor-in-Chief |
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Accepted by Executive Editor-in-Chief |
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2024-03-19 07:30 |
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Articles in Press |
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2024-03-19 07:30 |
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Publication Fee Transferred |
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Edit the Manuscript by Language Editor |
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Typeset the Manuscript |
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2024-04-15 05:43 |
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Publish the Manuscript Online |
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2024-05-09 13:59 |
ISSN |
1948-5204 (online) |
Open Access |
This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/ |
Copyright |
© The Author(s) 2024. Published by Baishideng Publishing Group Inc. All rights reserved. |
Article Reprints |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
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Permissions |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
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Publisher |
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
Website |
http://www.wjgnet.com |
Category |
Biochemistry & Molecular Biology |
Manuscript Type |
Editorial |
Article Title |
Interleukin-1β: Friend or foe for gastrointestinal cancers
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Manuscript Source |
Invited Manuscript |
All Author List |
Kullanat Khawkhiaw, Jutatip Panaampon, Thanit Imemkamon and Charupong Saengboonmee |
ORCID |
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Funding Agency and Grant Number |
Funding Agency |
Grant Number |
National Research Council of Thailand |
N41A640108 |
Mekong-Lancang Cooperation Special Fund |
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The Development and Promotion of Science and Technology Talents Project |
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Ministry of Education, Science, Sports, and Culture of Japan |
22K16327 |
Ministry of Education, Science, Sports, and Culture of Japan |
22K08482 |
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Corresponding Author |
Charupong Saengboonmee, MD, PhD, Assistant Professor, Doctor, Doctor, Department of Biochemistry, Faculty of Medicine, Khon Kaen University, 123 Mitraphap Highway, Khon Kaen 40002, Thailand. charusa@kku.ac.th |
Key Words |
Cancer; Gastrointestinal tract; Inflammation; Interleukin-1β; Tumor microenvironment |
Core Tip |
Interleukin-1β (IL-1β) is a pro-inflammatory cytokine primarily secreted by leukocytes to activate the immune response at the site of infection or inflammation. As tumor-promoting inflammation is one of the cancer hallmarks, IL-1β then plays central roles in tumor-promoting activities in many cancers, including cancers of the gastrointestinal tract. On the other hand, by activating and recruiting immune cells into the tumor microenvironments, IL-1β also has anti-tumor effects depending on the subtypes of immune cells that respond and infiltrate into the tumor site. Whether it could be a promising target for future therapeutic development is then discussed in this article. |
Publish Date |
2024-05-09 13:59 |
Citation |
Khawkhiaw K, Panaampon J, Imemkamon T, Saengboonmee C. Interleukin-1β: Friend or foe for gastrointestinal cancers. World J Gastrointest Oncol 2024; 16(5): 1676-1682 |
URL |
https://www.wjgnet.com/1948-5204/full/v16/i5/1676.htm |
DOI |
10.4251/wjgo.v16.i5.1676 |
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