ISSN |
2219-2808 (online) |
Open Access |
This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/ |
Copyright |
© The Author(s) 2024. Published by Baishideng Publishing Group Inc. All rights reserved. |
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Publisher |
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
Website |
http://www.wjgnet.com |
Category |
Biochemistry & Molecular Biology |
Manuscript Type |
Review |
Article Title |
Assessing the impact of concurrent high-fructose and high-saturated fat diets on pediatric metabolic syndrome: A review
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Manuscript Source |
Invited Manuscript |
All Author List |
Manuel Alejandro Vargas-Vargas, Marcela González-Montoya, Olin Torres-Isidro, Claudia Isabel García-Berumen, Omar Ortiz-Avila, Elizabeth Calderón-Cortés and Christian Cortés-Rojo |
ORCID |
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Funding Agency and Grant Number |
Funding Agency |
Grant Number |
Instituto de Ciencia, Tecnología e Innovación – Gobierno del Estado de Michoacán |
ICTI-PICIR23-063 |
Instituto de Ciencia, Tecnología e Innovación – Gobierno del Estado de Michoacán |
ICTI-PICIR23-028 |
Programa Proyectos de Investigación financiados 2024, Coordinación de Investigación Científica, Universidad Michoacana de San Nicolás de Hidalgo, México |
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Corresponding Author |
Christian Cortés-Rojo, BSc, MSc, PhD, Professor, Instituto de Investigaciones Químico – Biológicas, Universidad Michoacana de San Nicolás de Hidalgo, Edificio B-3, Ciudad Universitaria, Avenida Fco. J. Mujica, Morelia 58030, Michoacán, Mexico. christian.cortes@umich.mx |
Key Words |
Fructose; Saturated fat; Metabolic syndrome; Insulin resistance; Type 2 diabetes; Ultra processed foods; Children; Obesity; Dyslipidemia; Non-alcoholic fatty liver disease |
Core Tip |
High-fructose (HFr) or high-fat (HF) intake favors metabolic syndrome (MetS) development by different mechanisms. When combined, HFr exacerbates the effects of HF, leading to a faster and more severe MetS development. Combined HF + HFr is usually present in ultra-processed foods. However, there is a lack of studies in the pediatric population evaluating the impact of restricting the combined intake of carbohydrates and fat in MetS. We reviewed the mechanisms by which HF + HFr produces more severe MetS to support the need for studies targeting the combined intake of HF + HFr in pediatric population to improve the outcomes of different interventions against MetS. |
Publish Date |
2024-06-07 13:38 |
Citation |
<p>Vargas-Vargas MA, González-Montoya M, Torres-Isidro O, García-Berumen CI, Ortiz-Avila O, Calderón-Cortés E, Cortés-Rojo C. Assessing the impact of concurrent high-fructose and high-saturated fat diets on pediatric metabolic syndrome: A review. <i>World J Clin Pediatr</i> 2024; 13(2): 91478</p> |
URL |
https://www.wjgnet.com/2219-2808/full/v13/i2/91478.htm |
DOI |
https://dx.doi.org/10.5409/wjcp.v13.i2.91478 |