Publication Name	World Journal of Stem Cells
Manuscript ID	91489
Country	China

Received	2023-12-29 09:38
Peer-Review Started	2023-12-29 09:38
To Make the First Decision
Return for Revision	2024-02-12 20:33
Revised	2024-02-26 09:11
Second Decision	2024-04-01 06:37
Accepted by Journal Editor-in-Chief
Accepted by Executive Editor-in-Chief	2024-04-12 06:32
Articles in Press	2024-04-12 06:32
Publication Fee Transferred
Edit the Manuscript by Language Editor
Typeset the Manuscript	2024-05-13 09:18
Publish the Manuscript Online	2024-05-24 08:33

ISSN	1948-0210 (online)
Open Access	This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/Licenses/by-nc/4.0/
Copyright	© The Author(s) 2024. Published by Baishideng Publishing Group Inc. All rights reserved.
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Category	Cell & Tissue Engineering
Manuscript Type	Basic Study
Article Title	Effects of interleukin-10 treated macrophages on bone marrow mesenchymal stem cells via signal transducer and activator of transcription 3 pathway
Manuscript Source	Unsolicited Manuscript
All Author List	Meng-Hao Lyu, Ce Bian, Yi-Ping Dou, Kang Gao, Jun-Ji Xu and Pan Ma
ORCID	Author(s) ORCID Number Pan Ma http://orcid.org/0000-0001-6166-4714
Funding Agency and Grant Number	Funding Agency Grant Number National Natural Science Foundation of China 81974153, 82122015 Beijing Natural Science Foundation L222088
Corresponding Author	Pan Ma, PhD, Professor, Department of Dental Implantology, School of Stomatology, Capital Medical University, No. 4 Tiantan Xili, Beijing 100050, China. mapanxw@163.com
Key Words	Macrophages; Interleukin-10; Bone marrow mesenchymal stem cells; Signal transducer and activator of transcription 3; Inflammatory response
Core Tip	This study investigated the mechanism of interleukin-10 (IL-10) affecting macrophages in inflammatory environments, observed the effects of different macrophages on the biological behavior and osteogenic differentiation of bone marrow mesenchymal stem cells, and found that IL-10/signal transducer and activator of transcription 3 signaling plays a crucial role in promoting bone formation by affecting macrophages. This study provides a new strategy for solving the problem of poor osteogenesis in bone defect repair caused by an excessive inflammatory response in clinical work.
Publish Date	2024-05-24 08:33
Citation	<p>Lyu MH, Bian C, Dou YP, Gao K, Xu JJ, Ma P. Effects of interleukin-10 treated macrophages on bone marrow mesenchymal stem cells via signal transducer and activator of transcription 3 pathway. <i>World J Stem Cells</i> 2024; 16(5): 560-574</p>
URL	https://www.wjgnet.com/1948-0210/full/v16/i5/560.htm
DOI	https://dx.doi.org/10.4252/wjsc.v16.i5.560

Full Article (PDF)	WJSC-16-560-with-cover.pdf
Full Article (Word)	WJSC-16-560.docx
The ARRIVE Guidelines	91489-The ARRIVE guidelines.pdf
Manuscript File	91489_Auto_Edited-YJP.docx
Answering Reviewers	91489-Answering reviewers.pdf
Audio Core Tip	91489-Audio core tip.m4a
Biostatistics Review Certificate	91489-Biostatistics statement.pdf
Conflict-of-Interest Disclosure Form	91489-Conflict-of-interest statement.pdf
Copyright License Agreement	91489-Copyright license agreement.pdf
Approved Grant Application Form(s) or Funding Agency Copy of any Approval Document(s)	91489-Grant application form(s).pdf
Institutional Animal Care and Use Committee Approval Form or Document	91489-Institutional animal care and use committee statement.pdf
Non-Native Speakers of English Editing Certificate	91489-Language certificate.pdf
Peer-review Report	91489-Peer-review(s).pdf
Scientific Misconduct Check	91489-Bing-Wang JJ-2.png
Scientific Editor Work List	91489-Scientific editor work list.pdf
CrossCheck Report	91489-CrossCheck report.pdf