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Articles Published Processes
6/25/2024 10:11:57 AM | Browse: 252 | Download: 1187
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Received |
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2024-01-06 02:11 |
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Peer-Review Started |
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2024-01-06 02:11 |
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First Decision by Editorial Office Director |
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2024-03-09 06:33 |
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Return for Revision |
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2024-03-09 06:33 |
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Revised |
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2024-03-22 12:31 |
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Publication Fee Transferred |
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Second Decision by Editor |
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2024-04-15 10:06 |
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Second Decision by Editor-in-Chief |
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2024-04-21 16:34 |
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Final Decision by Editorial Office Director |
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2024-05-11 07:00 |
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Articles in Press |
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2024-05-11 07:00 |
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Edit the Manuscript by Language Editor |
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Typeset the Manuscript |
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2024-06-15 09:39 |
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Publish the Manuscript Online |
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2024-06-25 10:11 |
| ISSN |
1948-0210 (online) |
| Open Access |
This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/Licenses/by-nc/4.0/ |
| Copyright |
© The Author(s) 2024. Published by Baishideng Publishing Group Inc. All rights reserved. |
| Article Reprints |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
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| Permissions |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
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| Publisher |
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
| Website |
http://www.wjgnet.com |
| Category |
Cell Biology |
| Manuscript Type |
Basic Study |
| Article Title |
Mesenchymal stem cells-extracellular vesicles alleviate pulmonary fibrosis by regulating immunomodulators
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| Manuscript Source |
Unsolicited Manuscript |
| All Author List |
Ying Gao, Mei-Fang Liu, Yang Li, Xi Liu, Yu-Jie Cao, Qian-Fa Long, Jun Yu and Jian-Ying Li |
| ORCID |
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| Funding Agency and Grant Number |
| Funding Agency |
Grant Number |
| Xi’an Science and Technology Plan Project |
20200001YX001(1) |
| Xi’an Talent Plan - Elite (Innovative Talents) Project |
XAYC210062 |
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| Corresponding Author |
Jian-Ying Li, MD, Doctor, Doctor, Department of Respiratory and Critical Care Medicine, Xi’an Central Hospital, No. 163 West Fifth Road, Xi’an 710000, Shaanxi Province, China. l13572168322@163.com |
| Key Words |
Mesenchymal stem cells; Extracellular vesicles; Pulmonary fibrosis; Oxidative stress response; Epithelial mesenchymal transition |
| Core Tip |
This study unveils the innovative potential of mesenchymal stem cells-extracellular vesicles (MSC-EVs) in mitigating pulmonary fibrosis (PF). Notably, MSC-EVs effectively countered transforming growth factor-β1-induced fibrosis in A549 cells, showcasing a significant reduction in collagen I and alpha smooth muscle actin. The treatment exhibited a dual impact, alleviating oxidative stress and inflammatory responses in vitro. In PF mouse lungs, MSC-EVs demonstrated remarkable down-regulation of fibrotic markers and modulation of oxidative stress and inflammation. |
| Publish Date |
2024-06-25 10:11 |
| Citation |
Gao Y, Liu MF, Li Y, Liu X, Cao YJ, Long QF, Yu J, Li JY. Mesenchymal stem cells-extracellular vesicles alleviate pulmonary fibrosis by regulating immunomodulators. World J Stem Cells 2024; 16(6): 670-689 |
| URL |
https://www.wjgnet.com/1948-0210/full/v16/i6/670.htm |
| DOI |
https://dx.doi.org/10.4252/wjsc.v16.i6.670 |
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