Publication Name	World Journal of Gastroenterology
Manuscript ID	9154
Country	China

Received	2014-01-24 08:35
Peer-Review Started	2014-01-24 14:26
First Decision by Editorial Office Director
Return for Revision	2014-04-29 13:08
Revised	2014-05-12 20:15
Publication Fee Transferred
Second Decision by Editor	2014-06-26 17:03
Second Decision by Editor-in-Chief
Final Decision by Editorial Office Director	2014-06-26 17:24
Articles in Press	2014-06-26 17:52
Edit the Manuscript by Language Editor	2014-07-14 16:27
Typeset the Manuscript	2014-09-16 19:58
Publish the Manuscript Online	2014-10-01 20:25

ISSN	1007-9327 (print) and 2219-2840 (online)
Open Access
Copyright
Article Reprints	For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
Permissions	For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
Publisher	Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website	http://www.wjgnet.com

Category	Transplantation
Manuscript Type	Retrospective Study
Article Title	Risk factors for de novo hepatitis B infection in pediatric living donor liver transplantation
Manuscript Source	Unsolicited Manuscript
All Author List	Wei Rao, Man Xie, Tao Yang, Jian-Jun Zhang, Wei Gao, Yong-Lin Deng, Hong Zheng, Cheng Pan, Yi-He Liu and Zhong-Yang Shen
Funding Agency and Grant Number	Funding Agency Grant Number National High-tech R&D Program of China (863 Program) 2012AA021001
Corresponding Author	Zhong-Yang Shen, MD, PhD, Department of Organ Transplantation, Tianjin Key Laboratory of Organ Transplantation, Tianjin First Central Hospital, Fukang Road 24, Tianjin 300192, China. shenzhongyangmd@126.com
Key Words	Pediatric liver donor liver transplantation; Occult hepatitis B infection; De novo hepatitis B infection
Core Tip	We reported our experience of de novo hepatitis B virus (HBV) infection after pediatric living donor liver transplantation (LDLT), which showed that the incidence of de novo HBV infection in pediatric LDLT was 16.7% in our center. Among hepatitis B core antibody (HBcAb)-positive allografts, 43.7% were intrahepatic HBV DNA positive. Positive intrahepatic HBV DNA in allografts was predictive of de novo HBV infection after LDLT in children who were given HBcAb-positive allografts. Hepatitis B surface antibody/HBcAb positivity exhibited weak effectiveness in preventing children receiving HBcAb-positive allografts from de novo HBV infection. Lamivudine prophylaxis therapy is essential to prevent de novo HBV infection in pediatric patients from HBcAb-positive allografts with positive intrahepatic HBV DNA.
Publish Date	2014-10-01 20:25
Citation	Rao W, Xie M, Yang T, Zhang JJ, Gao W, Deng YL, Zheng H, Pan C, Liu YH, Shen ZY. Risk factors for de novo hepatitis B infection in pediatric living donor liver transplantation. World J Gastroenterol 2014; 20(36): 13159-13166
URL	http://www.wjgnet.com/1007-9327/full/v20/i36/13159.htm
DOI	http://dx.doi.org/10.3748/wjg.v20.i36.13159

Full Article (PDF)	WJG-20-13159.pdf
Full Article (Word)	WJG-20-13159.doc
Manuscript File	9154-Review.doc
Answering Reviewers	9154-Answering reviewers.pdf
Copyright License Agreement	9154-Copyright assignment.pdf
Non-Native Speakers of English Editing Certificate	9154-Language certificate.pdf
Peer-review Report	9154-Peer review.pdf
Scientific Misconduct Check	9154-CorssCheck.jpg
Scientific Editor Work List	9154-Scientific editor work list.pdf