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Articles Published Processes
4/25/2024 5:24:45 AM | Browse: 88 | Download: 244
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Received |
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2023-12-30 21:22 |
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Peer-Review Started |
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2023-12-30 21:22 |
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To Make the First Decision |
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Return for Revision |
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2024-01-23 06:21 |
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Revised |
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2024-02-05 21:06 |
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Second Decision |
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2024-03-11 02:45 |
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Accepted by Journal Editor-in-Chief |
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Accepted by Executive Editor-in-Chief |
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2024-03-18 06:04 |
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Articles in Press |
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2024-03-18 06:04 |
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Publication Fee Transferred |
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Edit the Manuscript by Language Editor |
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Typeset the Manuscript |
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2024-04-17 13:17 |
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Publish the Manuscript Online |
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2024-04-25 05:24 |
| ISSN |
1948-0210 (online) |
| Open Access |
This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/Licenses/by-nc/4.0/ |
| Copyright |
©The Author(s) 2024. Published by Baishideng Publishing Group Inc. All rights reserved. |
| Article Reprints |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
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| Permissions |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
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| Publisher |
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
| Website |
http://www.wjgnet.com |
| Category |
Medicine, Research & Experimental |
| Manuscript Type |
Basic Study |
| Article Title |
Effects of high glucose and severe hypoxia on the biological behavior of mesenchymal stem cells at various passages
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| Manuscript Source |
Invited Manuscript |
| All Author List |
Fatimah Almahasneh, Ejlal Abu-El-Rub, Ramada R Khasawneh and Rawan Almazari |
| ORCID |
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| Funding Agency and Grant Number |
| Funding Agency |
Grant Number |
| Deanship of Scientific Research, Yarmouk University, Jordan |
73/2022 |
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| Corresponding Author |
Ejlal Abu-El-Rub, PharmD, PhD, Assistant Professor, Department of Basic Medical Sciences, Faculty of Medicine, Yarmouk University, Irbid-Shafiq Irshidat Street, Irbid 21163, Jordan. ejlal.abuelrub@yu.edu.jo |
| Key Words |
Mesenchymal stem cells; High glucose; Hypoxia; Stressful microenvironment; Serial passage; Senescence; Apoptosis |
| Core Tip |
Mesenchymal stem cells (MSCs) are increasingly being used for the treatment of various diseases due to their immunomodulatory and regenerative properties, but serial passages needed for MSCs expansion and stress factors found in the diseased tissues may compromise their therapeutic potential. Investigating the effects of stress factors (high glucose and severe hypoxia) on the biological characteristics of MSCs at different passages will help optimize the clinical uses of MSCs and their expected outcomes. |
| Publish Date |
2024-04-25 05:24 |
| Citation |
Almahasneh F, Abu-El-Rub E, Khasawneh RR, Almazari R. Effects of high glucose and severe hypoxia on the biological behavior of mesenchymal stem cells at various passages. World J Stem Cells 2024; 16(4): 434-443 |
| URL |
https://www.wjgnet.com/1948-0210/full/v16/i4/434.htm |
| DOI |
https://dx.doi.org/10.4252/wjsc.v16.i4.434 |
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