Publication Name	World Journal of Gastroenterology
Manuscript ID	9161
Country	Taiwan

Received	2014-01-24 09:01
Peer-Review Started	2014-01-24 10:56
To Make the First Decision	2014-02-28 21:31
Return for Revision	2014-03-06 19:55
Revised	2014-03-26 16:29
Second Decision	2014-05-05 09:34
Accepted by Journal Editor-in-Chief
Accepted by Executive Editor-in-Chief	2014-05-05 10:04
Articles in Press	2014-05-23 09:39
Publication Fee Transferred
Edit the Manuscript by Language Editor
Typeset the Manuscript	2014-08-18 13:46
Publish the Manuscript Online	2014-08-29 11:57

ISSN	1007-9327 (print) and 2219-2840 (online)
Open Access
Copyright
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Publisher	Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website	http://www.wjgnet.com

Category	Gastroenterology & Hepatology
Manuscript Type	Case Control Study
Article Title	Lower serum folate is associated with development and invasiveness of gastric cancer
Manuscript Source	Invited Manuscript
All Author List	Teng-Yu Lee, En-Pei Chiang, Yin-Ting Shih, Hsien-Yuan Lane, Jaw-Town Lin and Chun-Ying Wu
Funding Agency and Grant Number	Funding Agency Grant Number National Science Council, Executive Yuan NSC-96-2314-B-075A-007 National Science Council, Executive Yuan NSC100-2628-B005-002MY4 National Science Council, Executive Yuan NSC101-2320-B-005-006-MY3 National Science Council, Executive Yuan NSC 101-2911-I​-005-301 ATU plan of the Ministry of Education, Taiwan
Corresponding Author	Correspondence to: Chun-Ying Wu, Professor, Faculty of Medicine, School of Medicine, National Yang-Ming University, 155, Sec. 2, Linong Street, Taipei 112, Taiwan. chun@vghtc.gov.tw
Key Words	Folic acid; Folate; Plasma; Metastasis; Invasion
Core Tip	Low folate status is involved in the development of gastric cancer, but the role of folate in invasiveness of gastric cancer remains unclear. In addition, although folate levels in blood may reflect the degree of folate depletion, an association between blood folate status and gastric cancer has not been established. In this case-control study, we found lower serum folate was significantly associated with gastric cancer development. Besides, in the patient cohort of gastric cancer, lower serum folate was significantly associated with invasive phenotypes such as serosal invasion, lymphatic invasion and liver metastasis. These findings warrant further study.
Publish Date	2014-08-29 11:57
Citation	Lee TY, Chiang EP, Shih YT, Lane HY, Lin JT, Wu CY. Lower serum folate is associated with development and invasiveness of gastric cancer. World J Gastroenterol 2014; 20(32): 11313-11320
URL	http://www.wjgnet.com/1007-9327/full/v20/i32/11313.htm
DOI	http://dx.doi.org/10.3748/wjg.v20.i32.11313

Full Article (PDF)	WJG-20-11313.pdf
Full Article (Word)	WJG-20-11313.doc
Manuscript File	9161-Review.doc
Answering Reviewers	9161-Answers reviewers.pdf
Biostatistics Review Certificate	Biostatistician_Review_Report_20140123235252.pdf
Copyright License Agreement	9161-Copyright assignment.pdf
Institutional Review Board Approval Form or Document	Ethics_Committee_20140123235208.pdf
Non-Native Speakers of English Editing Certificate	9161-Scientific editor work list.pdf
Peer-review Report	9161-Peer review.pdf
Scientific Editor Work List	9161-Scientific editor work list.pdf