Publication Name	World Journal of Clinical Oncology
Manuscript ID	91652
Country	China

Received	2024-01-02 16:17
Peer-Review Started	2024-01-02 16:17
To Make the First Decision
Return for Revision	2024-01-22 05:51
Revised	2024-02-08 21:38
Second Decision	2024-04-02 02:38
Accepted by Journal Editor-in-Chief
Accepted by Executive Editor-in-Chief	2024-04-02 03:28
Articles in Press	2024-04-02 03:28
Publication Fee Transferred
Edit the Manuscript by Language Editor
Typeset the Manuscript	2024-05-09 00:33
Publish the Manuscript Online	2024-05-21 07:25

ISSN	2218-4333 (online)
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Category	Oncology
Manuscript Type	Retrospective Study
Article Title	Human epidermal growth factor receptor 2 expression level and combined positive score can evaluate efficacy of advanced gastric cancer
Manuscript Source	Unsolicited Manuscript
All Author List	Xiao-Ting Ma, Kai Ou, Wen-Wei Yang, Bi-Yang Cao and Lin Yang
ORCID	Author(s) ORCID Number Xiao-Ting Ma http://orcid.org/0000-0003-1329-9761 Wen-Wei Yang http://orcid.org/0000-0002-7292-5980 Lin Yang http://orcid.org/0000-0002-4829-3119
Funding Agency and Grant Number	Funding Agency Grant Number Beijing CSCO Clinical Oncology Research Foundation No. Y-HH202102-0314
Corresponding Author	Lin Yang, MD, Director, Director, Doctor, Doctor, Department of Medical Oncology, National Cancer Center/National Clinical Research Center for Cancer/Cancer Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, No. 17 Panjiayuan Nanli, Chaoyang District, Beijing 100021, China. linyangcicams@126.com
Key Words	First line; Gastric cancer; Human epidermal growth factor receptor 2; Programmed cell death protein 1; Progression-free survival
Core Tip	For when considering non-positive human epidermal growth factor receptor 2 (HER2) advanced gastric cancer (AGC), combined positive score and HER2 expression are represent influencing factors for the treatment efficacy of AGC patients receiving immunotherapy combined with chemotherapy. Survival analysis with When using progression-free survival (PFS) as the end point, survival analysis suggested that the HER2 expression level was levels are suggestive of the efficacy of treatment featuring a programmed cell death protein 1 inhibitor combined with and chemotherapy. With the increase of HER2 expression, PFS also showed a tendency to prolong increase with an increase in HER2 expression.
Publish Date	2024-05-21 07:25
Citation	<p>Ma XT, Ou K, Yang WW, Cao BY, Yang L. Human epidermal growth factor receptor 2 expression level and combined positive score can evaluate efficacy of advanced gastric cancer. <i>World J Clin Oncol</i> 2024; 15(5): 635-643</p>
URL	https://www.wjgnet.com/2218-4333/full/v15/i5/635.htm
DOI	https://dx.doi.org/10.5306/wjco.v15.i5.635

Full Article (PDF)	WJCO-15-635-with-cover.pdf
Manuscript File	91652_Auto_Edited-YJP.docx
Answering Reviewers	91652-Answering reviewers.pdf
Audio Core Tip	91652-Audio core tip.mp3
Biostatistics Review Certificate	91652-Biostatistics statement.pdf
Conflict-of-Interest Disclosure Form	91652-Conflict-of-interest statement.pdf
Copyright License Agreement	91652-Copyright license agreement.pdf
Approved Grant Application Form(s) or Funding Agency Copy of any Approval Document(s)	91652-Grant application form(s).pdf
Signed Informed Consent Form(s) or Document(s)	91652-Informed consent statement.pdf
Institutional Review Board Approval Form or Document	91652-Institutional review board statement.pdf
Non-Native Speakers of English Editing Certificate	91652-Language certificate.pdf
Supplementary Material	91652-Supplementary material.pdf
Peer-review Report	91652-Peer-review(s).pdf
Scientific Misconduct Check	91652-Bing-Qu XL-2.jpg
Scientific Editor Work List	91652-Scientific editor work list.pdf
CrossCheck Report	91652-CrossCheck report.pdf