Publication Name	World Journal of Psychiatry
Manuscript ID	91726
Country	China

Received	2024-01-30 08:39
Peer-Review Started	2024-01-30 08:39
To Make the First Decision
Return for Revision	2024-04-30 02:57
Revised	2024-05-13 06:50
Second Decision	2024-06-04 02:45
Accepted by Journal Editor-in-Chief
Accepted by Executive Editor-in-Chief	2024-06-04 07:12
Articles in Press	2024-06-04 07:12
Publication Fee Transferred	2024-06-17 03:22
Edit the Manuscript by Language Editor	2024-06-21 02:02
Typeset the Manuscript	2024-06-28 08:07
Publish the Manuscript Online	2024-07-12 07:35

ISSN	2220-3206 (online)
Open Access	This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/Licenses/by-nc/4.0/
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Category	Psychiatry
Manuscript Type	Basic Study
Article Title	Gastrointestinal problems in a valproic acid-induced rat model of autism: From maternal intestinal health to offspring intestinal function
Manuscript Source	Unsolicited Manuscript
All Author List	Sha Li, Nan Zhang, Wang Li, Han-Lai Zhang and Xiao-Xi Wang
ORCID	Author(s) ORCID Number Xiao-Xi Wang http://orcid.org/0000-0003-2710-9906
Funding Agency and Grant Number	Funding Agency Grant Number National Natural Science Foundation of China 82305035
Corresponding Author	Xiao-Xi Wang, PhD, Research Assistant, China Academy of Chinese Medical Sciences, Institute of Acupuncture and Moxibustion, No. 16 South Street, Dongzhimen Nei, Beijing 100000, China. wxxcacms@163.com
Key Words	Autism spectrum disorder; Gastrointestinal problems; Gut microbiota; Intestinal inflammation; Intestinal motility
Core Tip	In the previous studies, the etiology and treatment of gastrointestinal (GI) tract disease in autistic patients have not received sufficient attention. Thus, our research focus more on GI problems in autism, and use the valproic acid model to explore the relationship between maternal gut microbiota and inflammation and offsprings GI problems. In this study we found that valproic acid exposure during pregnancy was related to pathological maternal intestinal changes and alterations in maternal gut microbiota. Our findings will provide more evidence and possibilities for autism intervention.
Publish Date	2024-07-12 07:35
Citation	<p>Li S, Zhang N, Li W, Zhang HL, Wang XX. Gastrointestinal problems in a valproic acid-induced rat model of autism: From maternal intestinal health to offspring intestinal function. <i>World J Psychiatry</i> 2024; 14(7): 1095-1105</p>
URL	https://www.wjgnet.com/2220-3206/full/v14/i7/1095.htm
DOI	https://dx.doi.org/10.5498/wjp.v14.i7.1095

Full Article (PDF)	WJP-14-1095-with-cover.pdf
Full Article (Word)	WJP-14-1095.docx
The ARRIVE Guidelines	91726-The ARRIVE Guidelines.pdf
Manuscript File	91726_Auto_Edited-YJP_WangTQ.docx
Answering Reviewers	91726-answering-reviewers.pdf
Audio Core Tip	91726-audio.mp3
Biostatistics Review Certificate	91726-biostatistics-statement.pdf
Conflict-of-Interest Disclosure Form	91726-conflict-of-interest-statement.pdf
Copyright License Agreement	91726-copyright-assignment.pdf
Approved Grant Application Form(s) or Funding Agency Copy of any Approval Document(s)	91726-foundation-statement.pdf
Institutional Animal Care and Use Committee Approval Form or Document	91726-institutional-animal-care-and-use-committee-statement.pdf
Non-Native Speakers of English Editing Certificate	91726-non-native-speakers.pdf
Peer-review Report	91726-peer-reviews.pdf
Scientific Misconduct Check	91726-scientific-misconduct-check.png
Scientific Editor Work List	91726-scientific-editor-work-list.pdf
CrossCheck Report	91726-crosscheck-report.pdf