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Articles Published Processes
5/23/2024 9:40:29 AM | Browse: 178 | Download: 781
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Received |
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2024-01-04 07:18 |
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Peer-Review Started |
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2024-01-04 07:18 |
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First Decision by Editorial Office Director |
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2024-03-31 04:36 |
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Return for Revision |
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2024-03-31 04:49 |
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Revised |
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2024-04-10 07:43 |
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Publication Fee Transferred |
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Second Decision by Editor |
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2024-04-22 02:55 |
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Second Decision by Editor-in-Chief |
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Final Decision by Editorial Office Director |
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2024-04-22 05:51 |
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Articles in Press |
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2024-04-22 05:51 |
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Edit the Manuscript by Language Editor |
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Typeset the Manuscript |
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2024-05-14 07:42 |
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Publish the Manuscript Online |
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2024-05-23 09:40 |
| ISSN |
1948-9366 (online) |
| Open Access |
This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/ |
| Copyright |
©The Author(s) 2024. Published by Baishideng Publishing Group Inc. All rights reserved. |
| Article Reprints |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
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| Permissions |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
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| Publisher |
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
| Website |
http://www.wjgnet.com |
| Category |
Gastroenterology & Hepatology |
| Manuscript Type |
Case Report |
| Article Title |
Metastatic stomach lymphoepithelioma-like carcinoma and immune checkpoint inhibitor therapy: A case report
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| Manuscript Source |
Unsolicited Manuscript |
| All Author List |
Guo-Feng Chen, Jun Wang, Yu Yan, Song Xu and Jian Chen |
| ORCID |
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| Funding Agency and Grant Number |
| Funding Agency |
Grant Number |
| Zhejiang Provincial Key Project of Research and Development |
No. 2019C03043 |
| National Natural Science Foundation of China |
No. 82203452 |
| Health Science and Technology Plan of Zhejiang Province |
No. 2022RC165 |
| Clinical Research Fund of Zhejiang Medical Association |
No. 2021ZYC-A68 |
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| Corresponding Author |
Jian Chen, MD, PhD, Director, Director, Department of Gastroenterology Surgery, The Second Affiliated Hospital, Zhejiang University School of Medicine, No. 88 Jiefang Road, Hangzhou 310000, Zhejiang Province, China. zrchenjian@zju.edu.cn |
| Key Words |
Stomach neoplasm; Pulmonary lymphoepithelioma-like carcinoma; Metastasis; Immune checkpoint inhibitor; Case report |
| Core Tip |
Pulmonary lymphoepithelioma-like carcinoma (PLELC) is a rare type of non-small-cell lung cancer. Stomach LELC metastasis secondary to PLELC has not been reported recently. We present a 64-year-old female patient who was admitted to our hospital for a regular gastroscopy examination with a 6-year history of surgical resection for left PLELC. After proximal gastrectomy, histopathological examination showed a poorly differentiated carcinoma with prominent lymphoplasmacytic infiltration, suggesting stomach LELC metastasis. Tumor programmed cell death ligand 1 (PD-L1) expression showed a tumor proportion score of 98% and a combined positive score of 100. After discharge, this patient underwent PD-1 inhibitor treatment for ten cycles and has not experienced tumor recurrence. These findings suggest that for gastric LELC metastasis, PD-1 inhibitor therapy could become a potential therapeutic approach. |
| Publish Date |
2024-05-23 09:40 |
| Citation |
Chen GF, Wang J, Yan Y, Xu S, Chen J. Metastatic stomach lymphoepithelioma-like carcinoma and immune checkpoint inhibitor therapy: A case report. World J Gastrointest Surg 2024; 16(5): 1436-1442 |
| URL |
https://www.wjgnet.com/1948-9366/full/v16/i5/1436.htm |
| DOI |
https://dx.doi.org/10.4240/wjgs.v16.i5.1436 |
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