BPG is committed to discovery and dissemination of knowledge
Articles Published Processes
8/8/2024 4:58:17 AM | Browse: 82 | Download: 612
 |
Received |
|
2024-01-05 07:18 |
|
Peer-Review Started |
|
2024-01-05 07:18 |
|
First Decision by Editorial Office Director |
|
2024-05-24 06:17 |
|
Return for Revision |
|
2024-05-24 06:17 |
|
Revised |
|
2024-06-06 09:25 |
|
Publication Fee Transferred |
|
2024-07-02 08:55 |
|
Second Decision by Editor |
|
2024-06-25 02:44 |
 |
Second Decision by Editor-in-Chief |
|
|
|
Final Decision by Editorial Office Director |
|
2024-06-25 06:46 |
|
Articles in Press |
|
2024-06-25 06:46 |
|
Edit the Manuscript by Language Editor |
|
2024-07-11 21:34 |
|
Typeset the Manuscript |
|
2024-07-16 03:52 |
|
Publish the Manuscript Online |
|
2024-08-08 04:58 |
| ISSN |
1948-5204 (online) |
| Open Access |
This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/ |
| Copyright |
© The Author(s) 2024. Published by Baishideng Publishing Group Inc. All rights reserved. |
| Article Reprints |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
|
| Permissions |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
|
| Publisher |
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
| Website |
http://www.wjgnet.com |
| Category |
Gastroenterology & Hepatology |
| Manuscript Type |
Basic Study |
| Article Title |
Insulin-like growth factor 2 targets IGF1R signaling transduction to facilitate metastasis and imatinib resistance in gastrointestinal stromal tumors
|
| Manuscript Source |
Unsolicited Manuscript |
| All Author List |
De-Gang Li, Jia-Peng Jiang, Fan-Ye Chen, Wei Wu, Jun Fu, Gong-He Wang and Yu-Bo Li |
| ORCID |
|
| Funding Agency and Grant Number |
|
| Corresponding Author |
Yu-Bo Li, MM, Associate Chief Physician, Department of Gastrointestinal and Anorectal Surgery, The First Affiliated Hospital of Guangxi University of Chinese Medicine, No. 89-9 Dongge Road, Nanning 530023, Guangxi Zhuang Autonomous Region, China. gzyzyyfygc@126.com |
| Key Words |
Insulin-like growth factor 2; Gastrointestinal stromal tumors; IGF1R; Glycolysis; Imatinib resistance |
| Core Tip |
Our study examined that insulin-like growth factor 2 (IGF2) regulated metastasis and imatinib resistance in gastrointestinal stromal tumors (GIST). IGF2 interacted with IGF1R to regulate the glycolysis. Our results certified that IGF2 targeting IGF1R signaling improved metastasis and imatinib chemosensitivity via driving glycolysis in GIST and revealed that IGF2 might be used for reversing the GIST patients’ imatinib resistance. |
| Publish Date |
2024-08-08 04:58 |
| Citation |
Li DG, Jiang JP, Chen FY, Wu W, Fu J, Wang GH, Li YB. Insulin-like growth factor 2 targets IGF1R signaling transduction to facilitate metastasis and imatinib resistance in gastrointestinal stromal tumors. World J Gastrointest Oncol 2024; 16(8): 3585-3599 |
| URL |
https://www.wjgnet.com/1948-5204/full/v16/i8/3585.htm |
| DOI |
https://dx.doi.org/10.4251/wjgo.v16.i8.3585 |
© 2004-2026 Baishideng Publishing Group Inc. All rights reserved. 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
California Corporate Number: 3537345
