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Articles Published Processes
4/19/2024 8:45:27 AM | Browse: 78 | Download: 239
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Received |
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2024-01-05 09:42 |
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Peer-Review Started |
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2024-01-05 09:42 |
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To Make the First Decision |
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Return for Revision |
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2024-01-15 03:41 |
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Revised |
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2024-01-24 16:39 |
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Second Decision |
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2024-03-28 01:51 |
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Accepted by Journal Editor-in-Chief |
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Accepted by Executive Editor-in-Chief |
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2024-03-28 02:21 |
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Articles in Press |
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2024-03-28 02:21 |
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Publication Fee Transferred |
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Edit the Manuscript by Language Editor |
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Typeset the Manuscript |
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2024-04-07 23:01 |
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Publish the Manuscript Online |
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2024-04-19 08:45 |
| ISSN |
1007-9327 (print) and 2219-2840 (online) |
| Open Access |
This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/Licenses/by-nc/4.0/ |
| Copyright |
© The Author(s) 2024. Published by Baishideng Publishing Group Inc. All rights reserved. |
| Article Reprints |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
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| Permissions |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
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| Publisher |
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
| Website |
http://www.wjgnet.com |
| Category |
Oncology |
| Manuscript Type |
Editorial |
| Article Title |
Understanding autoimmune pancreatitis: Clinical features, management challenges, and association with malignancies
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| Manuscript Source |
Invited Manuscript |
| All Author List |
Grigorios Christodoulidis, Marina Nektaria Kouliou and Konstantinos Eleftherios Koumarelas |
| ORCID |
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| Funding Agency and Grant Number |
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| Corresponding Author |
Grigorios Christodoulidis, MD, PhD, Academic Editor, Department of General Surgery, University Hospital of Larissa, University of Thessaly, Biopolis Campus, Larissa 41110, Greece. gregsurg09@gmail.com |
| Key Words |
Autoimmune pancreatitis; Immunoglobulin G4-related disease; Pancreatic cancer; Surgery |
| Core Tip |
Autoimmune pancreatitis (AIP) is a unique form of pancreatitis, categorized into AIP-1 and AIP-2, with distinct clinical characteristics and associations. AIP-1, linked to elevated immunoglobulin G4 (IgG4) levels, exhibits higher relapse rates and predominantly affects older males, while AIP-2 is less common and associated with inflammatory bowel disease. Recognized as a manifestation of IgG4-related systemic disease, AIP poses an increased risk of malignancies, especially gastric, colorectal, and bladder cancers. Despite ongoing debates about the association with pancreatic cancer, careful diagnostic evaluation, including biopsy and response to steroids, is crucial for informed decision-making regarding surgery. AIP patients may have concurrent PanINs but generally experience better long-term outcomes compared to pancreatic cancer patients. Steroids remain the primary treatment, and emerging biomarkers like interferon alpha and interleukin-33 offer promising avenues for monitoring and managing AIP. |
| Publish Date |
2024-04-19 08:45 |
| Citation |
Christodoulidis G, Kouliou MN, Koumarelas KE. Understanding autoimmune pancreatitis: Clinical features, management challenges, and association with malignancies. World J Gastroenterol 2024; 30 (15)：2091-2095 |
| URL |
https://www.wjgnet.com/1007-9327/full/v30/i15/2091.htm |
| DOI |
https://dx.doi.org/10.3748/wjg.v30.i15.2091 |
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