| ISSN |
2222-0682 (online) |
| Open Access |
This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/ |
| Copyright |
© The Author(s) 2024. Published by Baishideng Publishing Group Inc. All rights reserved. |
| Article Reprints |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
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| Permissions |
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| Publisher |
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
| Website |
http://www.wjgnet.com |
| Category |
Gastroenterology & Hepatology |
| Manuscript Type |
Retrospective Cohort Study |
| Article Title |
Early versus delayed necrosectomy in pancreatic necrosis: A population-based cohort study on readmission, healthcare utilization, and in-hospital mortality
|
| Manuscript Source |
Invited Manuscript |
| All Author List |
Hassam Ali, Faisal Inayat, Vinay Jahagirdar, Fouad Jaber, Arslan Afzal, Pratik Patel, Hamza Tahir, Muhammad Sajeel Anwar, Attiq Ur Rehman, Muhammad Sarfraz, Ahtshamullah Chaudhry, Gul Nawaz, Dushyant Singh Dahiya, Amir H Sohail and Muhammad Aziz |
| ORCID |
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| Funding Agency and Grant Number |
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| Corresponding Author |
Faisal Inayat, MBBS, Research Scientist, Department of Internal Medicine, Allama Iqbal Medical College, Allama Shabbir Ahmad Usmani Road, Faisal Town, Lahore 54550, Punjab, Pakistan. faisalinayat@hotmail.com |
| Key Words |
Acute necrotizing pancreatitis; Pancreatic necrosis; Early necrosectomy; Delayed necrosectomy; Readmission, Healthcare costs; Mortality |
| Core Tip |
Clinical evidence regarding the impact of necrosectomy timing on patient outcomes and healthcare costs remains limited. Utilizing propensity-matched cohorts, this nationwide study evaluates the clinical and economic implications of early versus delayed necrosectomy in patients with pancreatic necrosis. Our findings show that early intervention within 48 hours is associated with lower rates of mechanical ventilation, septic shock, and in-hospital mortality. Early necrosectomy also results in substantial cost savings and shorter hospital stays. Intriguingly, the timing of the procedure does not significantly influence the 30-day readmission hazard ratio. These results contribute to the ongoing debate on the optimal timing of necrosectomy, offering evidence-based insights that could improve patient outcomes. |
| Publish Date |
2024-06-25 09:25 |
| Citation |
<p>Ali H, Inayat F, Jahagirdar V, Jaber F, Afzal A, Patel P, Tahir H, Anwar MS, Rehman AU, Sarfraz M, Chaudhry A, Nawaz G, Dahiya DS, Sohail AH, Aziz M. Early versus delayed necrosectomy in pancreatic necrosis: A population-based cohort study on readmission, healthcare utilization, and in-hospital mortality. <i>World J Methodol</i> 2024; 14(3): 91810</p> |
| URL |
https://www.wjgnet.com/2222-0682/full/v14/i3/91810.htm |
| DOI |
https://dx.doi.org/10.5662/wjm.v14.i3.91810 |
