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Articles Published Processes
6/15/2024 2:49:02 AM | Browse: 53 | Download: 243
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Received |
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2024-01-08 16:00 |
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Peer-Review Started |
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2024-01-08 16:00 |
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To Make the First Decision |
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Return for Revision |
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2024-02-29 19:41 |
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Revised |
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2024-03-05 02:53 |
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Second Decision |
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2024-04-10 02:34 |
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Accepted by Journal Editor-in-Chief |
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Accepted by Executive Editor-in-Chief |
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2024-04-10 04:55 |
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Articles in Press |
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2024-04-10 04:55 |
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Publication Fee Transferred |
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Edit the Manuscript by Language Editor |
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Typeset the Manuscript |
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2024-05-14 12:35 |
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Publish the Manuscript Online |
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2024-06-15 02:49 |
| ISSN |
1948-5204 (online) |
| Open Access |
This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/Licenses/by-nc/4.0/ |
| Copyright |
© The Author(s) 2024. Published by Baishideng Publishing Group Inc. All rights reserved. |
| Article Reprints |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
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| Permissions |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
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| Publisher |
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
| Website |
http://www.wjgnet.com |
| Category |
Oncology |
| Manuscript Type |
Editorial |
| Article Title |
Mixed neuroendocrine and adenocarcinoma of gastrointestinal tract: A complex diagnosis and therapeutic challenge
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| Manuscript Source |
Invited Manuscript |
| All Author List |
Santosh Shenoy |
| ORCID |
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| Funding Agency and Grant Number |
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| Corresponding Author |
Santosh Shenoy, FACS, MD, Professor, Department of General Surgery, Kansas City VA Medical Center, University of Missouri - Kansas City, 4801 E Linwood, Kansas City, MO 64128, United States. shenoy2009@hotmail.com |
| Key Words |
Tumor plasticity; Cell reprograming; Mixed adeno-neuroendocrine cancer; Mixed neuroendocrine and non-neuroendocrine neoplasm; Mixed adenocarcinoma and neuroendocrine carcinoma |
| Core Tip |
Mixed neuroendocrine and non-neuroendocrine neoplasms and mixed adeno-neuroendocrine cancer of the gastrointestinal system are a rare heterogeneous group of tumors with high malignant potential, rapid growth, and poor prognosis. The occurrence of cells with both neuroendocrine and non-neuroendocrine morphological features co-exist in varying amounts, and these tumors occur in almost all organs. The origin of these mixed cancers is not clearly defined but may be the result of certain genetic alterations and growth stimulation by the neuroendocrine peptides produced by neuroendocrine component. Regardless of the organ of origin, these tumors portend poor prognosis with increased proportion of neuroendocrine component. Multidisciplinary services and strategies are required for the management of these mixed malignancies to provide the best oncological outcomes. |
| Publish Date |
2024-06-15 02:49 |
| Citation |
<p>Shenoy S. Mixed neuroendocrine and adenocarcinoma of gastrointestinal tract: A complex diagnosis and therapeutic challenge. <i>World J Gastrointest Oncol</i> 2024; 16(6): 2295-2299</p> |
| URL |
https://www.wjgnet.com/1948-5204/full/v16/i6/2295.htm |
| DOI |
https://dx.doi.org/10.4251/wjgo.v16.i6.2295 |
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