Publication Name	World Journal of Orthopedics
Manuscript ID	91898
Country	United States

Received	2024-01-08 16:20
Peer-Review Started	2024-01-08 16:20
To Make the First Decision
Return for Revision	2024-01-28 05:13
Revised	2024-01-29 02:46
Second Decision	2024-03-01 02:56
Accepted by Journal Editor-in-Chief
Accepted by Executive Editor-in-Chief	2024-03-01 07:17
Articles in Press	2024-03-01 07:17
Publication Fee Transferred
Edit the Manuscript by Language Editor	2024-03-06 04:24
Typeset the Manuscript	2024-04-10 02:10
Publish the Manuscript Online	2024-04-16 08:04

ISSN	2218-5836 (online)
Open Access	This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/
Copyright	© The Author(s) 2024. Published by Baishideng Publishing Group Inc. All rights reserved.
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Website	http://www.wjgnet.com

Category	Orthopedics
Manuscript Type	Editorial
Article Title	Effect of weight-adjusted antimicrobial antibiotic prophylaxis on post-operative dosage and surgical site infections incidence in total joint arthroplasty
Manuscript Source	Invited Manuscript
All Author List	Ashim Gupta and Vijay Kumar Jain
ORCID	Author(s) ORCID Number Ashim Gupta http://orcid.org/0000-0003-1224-2755 Vijay Kumar Jain http://orcid.org/0000-0003-4164-7380
Funding Agency and Grant Number
Corresponding Author	Ashim Gupta, MS, PhD, Founder and CEO, President, President, Professor, Department of Orthopaedics and Regenerative Medicine, Future Biologics, 2505 Newpoint Pkwy, Lawrenceville, GA 30043, United States. ashim6786@gmail.com
Key Words	Antibiotics; Antimicrobial prophylaxis; Weight-adjusted; Surgical site infections; Total joint arthroplasty; Knee arthroplasty; Hip arthroplasty
Core Tip	This editorial emphasizes on evaluating the efficacy of weight-adjusted antimicrobial antibiotic prophylaxis regime on the incidence of surgical site infections and post-operative dosage reduction compared to conventionally used regime during total joint arthroplasty. The results demonstrated similar efficacy between both regimes with respect to the incidence of SSI. In addition, weight-adjustment led to reduced post-operative dosage and has the potential to reduce chances of achieving lower therapeutic concentration, drug resistance, drug toxicity and costs.
Publish Date	2024-04-16 08:04
Citation	Gupta A, Jain VK. Effect of weight-adjusted antimicrobial antibiotic prophylaxis on post-operative dosage and surgical site infections incidence in total joint arthroplasty. World J Orthop 2024; 15(4): 318-320
URL	https://www.wjgnet.com/2218-5836/full/v15/i4/318.htm
DOI	https://dx.doi.org/10.5312/wjo.v15.i4.318

Full Article (PDF)	WJO-15-318-with-cover.pdf
Manuscript File	91898-Review-FilipodiaCL.docx
Answering Reviewers	91898-Answering reviewers.pdf
Audio Core Tip	91898-Audio core tip.mp3
Conflict-of-Interest Disclosure Form	91898-Conflict-of-interest statement.pdf
Copyright License Agreement	91898-Copyright license agreement.pdf
Peer-review Report	91898-Peer-review(s).pdf
Scientific Editor Work List	91898-Scientific editor work list.pdf
CrossCheck Report	91898-CrossCheck report.pdf