Publication Name	World Journal of Gastrointestinal Oncology
Manuscript ID	91919
Country	China

Received	2024-01-09 12:09
Peer-Review Started	2024-01-09 12:09
To Make the First Decision
Return for Revision	2024-01-26 06:02
Revised	2024-02-05 14:51
Second Decision	2024-04-08 02:45
Accepted by Journal Editor-in-Chief
Accepted by Executive Editor-in-Chief	2024-04-08 05:19
Articles in Press	2024-04-08 05:19
Publication Fee Transferred
Edit the Manuscript by Language Editor
Typeset the Manuscript	2024-05-14 12:40
Publish the Manuscript Online	2024-06-15 02:49

ISSN	1948-5204 (online)
Open Access	This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/
Copyright	© The Author(s) 2024. Published by Baishideng Publishing Group Inc. All rights reserved.
Article Reprints	For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
Permissions	For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
Publisher	Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website	http://www.wjgnet.com

Category	Gastroenterology & Hepatology
Manuscript Type	Clinical and Translational Research
Article Title	Socioeconomic traits and the risk of Barrett’s esophagus and gastroesophageal reflux disease: A Mendelian randomization study
Manuscript Source	Unsolicited Manuscript
All Author List	Yu-Xin Liu, Cheng-Li Bin, Lu Zhang, Wen-Tao Yang and Bai-Ping An
ORCID	Author(s) ORCID Number Yu-Xin Liu http://orcid.org/0009-0005-9738-2336 Cheng-Li Bin http://orcid.org/0009-0009-6129-689X Lu Zhang http://orcid.org/0009-0005-5226-2453 Wen-Tao Yang http://orcid.org/0009-0005-2595-3363 Bai-Ping An http://orcid.org/0000-0002-2637-2676
Funding Agency and Grant Number	Funding Agency Grant Number Sichuan Research Center for Coordinated Development of TCM Culture 2022XT12
Corresponding Author	Bai-Ping An, Doctor, Attending Doctor, Department of Oncology, Hospital of Chengdu University of Traditional Chinese Medicine, No. 39 Shi-er-Qiao Road, Chengdu 610072, Sichuan Province, China. anbaiping@cdutcm.edu.cn
Key Words	Socioeconomic status; Gastroesophageal reflux disease; Barrett’s esophagus; Two-step Mendelian randomization; Multivariate Mendelian randomization
Core Tip	This study linked the Townsend Deprivation Index at recruitment to a higher risk of gastroesophageal reflux disease (GERD), while household income and educational attainment protected against GERD. Additionally, our study provided a deeper understanding of the causal effects of educational attainment and household income on GERD and Barrett’s esophagus. Sleep, major depressive disorder, and smoking mediated the relationship between socioeconomic status and GERD or Barret’s esophagus. This Mendelian randomization study has significant public health implications for primary and secondary prevention of esophageal cancer.
Publish Date	2024-06-15 02:49
Citation	<p>Liu YX, Bin CL, Zhang L, Yang WT, An BP. Socioeconomic traits and the risk of Barrett’s esophagus and gastroesophageal reflux disease: A Mendelian randomization study. <i>World J Gastrointest Oncol</i> 2024; 16(6): 2631-2645</p>
URL	https://www.wjgnet.com/1948-5204/full/v16/i6/2631.htm
DOI	https://dx.doi.org/10.4251/wjgo.v16.i6.2631

Full Article (PDF)	WJGO-16-2631-with-cover.pdf
Manuscript File	91919_Auto_Edited-YJP.docx
Answering Reviewers	91919-answering-reviewers.pdf
Audio Core Tip	91919-audio.mp3
Biostatistics Review Certificate	91919-biostatistics-statement.pdf
Conflict-of-Interest Disclosure Form	91919-conflict-of-interest-statement.pdf
Copyright License Agreement	91919-copyright-assignment.pdf
Approved Grant Application Form(s) or Funding Agency Copy of any Approval Document(s)	91919-foundation-statement.pdf
Non-Native Speakers of English Editing Certificate	91919-non-native-speakers.pdf
Supplementary Material	91919-supplementary-material.pdf
Peer-review Report	91919-peer-reviews.pdf
Scientific Misconduct Check	91919-scientific-misconduct-check.png
Scientific Editor Work List	91919-scientific-editor-work-list.pdf
CrossCheck Report	91919-crosscheck-report.png
CrossCheck Report	91919-crosscheck-report.pdf