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Articles Published Processes
8/21/2024 11:22:32 PM | Browse: 183 | Download: 860
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Received |
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2024-01-10 13:13 |
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Peer-Review Started |
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2024-01-10 13:13 |
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First Decision by Editorial Office Director |
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2024-04-10 05:59 |
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Return for Revision |
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2024-04-10 05:59 |
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Revised |
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2024-04-27 18:36 |
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Publication Fee Transferred |
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2024-07-16 08:57 |
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Second Decision by Editor |
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2024-05-17 02:44 |
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Second Decision by Editor-in-Chief |
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Final Decision by Editorial Office Director |
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2024-05-17 07:39 |
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Articles in Press |
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2024-05-17 07:39 |
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Edit the Manuscript by Language Editor |
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Typeset the Manuscript |
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2024-07-19 00:40 |
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Publish the Manuscript Online |
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2024-08-21 23:22 |
| ISSN |
1948-5182 (online) |
| Open Access |
This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/Licenses/by-nc/4.0/ |
| Copyright |
© The Author(s) 2024. Published by Baishideng Publishing Group Inc. All rights reserved. |
| Article Reprints |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
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| Permissions |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
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| Publisher |
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
| Website |
http://www.wjgnet.com |
| Category |
Gastroenterology & Hepatology |
| Manuscript Type |
Retrospective Cohort Study |
| Article Title |
Alpha-1 antitrypsin deficiency and Pi*Z allele as important co-factors in the development of liver fibrosis
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| Manuscript Source |
Unsolicited Manuscript |
| All Author List |
Ana Isabel Ferreira, Catarina Guimarães, Vitor Macedo Silva, Sofia Xavier, Joana Magalhães and José Cotter |
| ORCID |
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| Funding Agency and Grant Number |
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| Corresponding Author |
Ana Isabel Ferreira, MD, Medical Assistant, Department of Gastroenterology, Hospital da Senhora da Oliveira - Guimarães, Rua dos Cutileiros 114, Creixomil, Guimarães 4835-044, Portugal. ai.voferreira@gmail.com |
| Key Words |
Alpha-1 antitrypsin deficiency; Liver fibrosis; Nonalcoholic fatty liver disease fibrosis score; Fibrosis-4 index; Liver stiffness measurement |
| Core Tip |
Patients with alpha-1 antitrypsin deficiency (AATD) who have more than 50 years of age and had a diagnosis after 41 years of age are at increased risk of developing liver fibrosis, as well as those who have at least one Pi*Z allele. In patients with AATD, the presence of metabolic risk factors, such as hypertension, type 2 diabetes mellitus, and dyslipidaemia, and regular alcohol consumption, should be closely monitored and controlled, since these are important risk factors for the development of liver fibrosis. |
| Publish Date |
2024-08-21 23:22 |
| Citation |
Ferreira AI, Guimarães C, Macedo Silva V, Xavier S, Magalhães J, Cotter J. Alpha-1 antitrypsin deficiency and Pi*Z allele as important co-factors in the development of liver fibrosis. World J Hepatol 2024; 16(8): 1099-1110
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| URL |
https://www.wjgnet.com/1948-5182/full/v16/i8/1099.htm |
| DOI |
https://dx.doi.org/10.4254/wjh.v16.i8.1099 |
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