Publication Name	World Journal of Gastroenterology
Manuscript ID	9197
Country	China

Received	2014-01-27 10:14
Peer-Review Started	2014-02-08 13:53
To Make the First Decision	2014-05-29 19:10
Return for Revision	2014-06-03 16:12
Revised	2014-04-02 14:06
Second Decision	2014-07-22 16:48
Accepted by Journal Editor-in-Chief
Accepted by Executive Editor-in-Chief	2014-07-22 17:05
Articles in Press	2014-07-22 18:27
Publication Fee Transferred
Edit the Manuscript by Language Editor	2014-07-26 11:29
Typeset the Manuscript	2014-10-08 20:01
Publish the Manuscript Online	2014-10-20 18:35

ISSN	1007-9327 (print) and 2219-2840 (online)
Open Access
Copyright
Article Reprints	For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
Permissions	For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
Publisher	Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website	http://www.wjgnet.com

Category	Gastroenterology & Hepatology
Manuscript Type	Topic Highlights
Article Title	Impact of psychological stress on irritable bowel syndrome
Manuscript Source	Invited Manuscript
All Author List	Hong-Yan Qin, Chung-Wah Cheng, Xu-Dong Tang and Zhao-Xiang Bian
Funding Agency and Grant Number
Corresponding Author	Zhao-Xiang Bian, MD, PhD, Professor, Lab of Brain and Gut Research, School of Chinese Medicine, Hong Kong Baptist University, No 7 of Baptist Road, Kowloon Tong, Hong Kong. bzxiang@hkbu.edu.hk
Key Words	Psychological stress; Irritable bowel syndrome; Microbiota-gut-brain axis; Immune activation
Core Tip	Evidence from both clinical and experimental studies showed that psychological stress, acute or chronic, occurring in early life or adulthood, has marked impact on intestinal sensitivity, motility, secretion and permeability, and the underlying mechanism has a close correlation with mucosal immune activation, alteration in central nervous system, peripheral neurons and gastrointestinal microbiota. This review provides an overview about how psychological stress contributes to the development of irritable bowel syndrome (IBS) and aggravation of IBS symptoms, and informs a more comprehensive approach to the management of IBS.
Publish Date	2014-10-20 18:35
Citation	Qin HY, Cheng CW, Tong XD, Bian ZX. Impact of psychological stress on irritable bowel syndrome. World J Gastroenterol 2014; 20(39): 14126-14131
URL	http://www.wjgnet.com/1007-9327/full/v20/i39/14126.htm
DOI	http://dx.doi.org/10.3748/wjg.v20.i39.14126

Full Article (PDF)	WJG-20-14126.pdf
Full Article (Word)	WJG-20-14126.doc
Manuscript File	9197-Review.doc
Answering Reviewers	9197-Answering reviewers.pdf
Copyright License Agreement	9197-Copyright assignment.pdf
Non-Native Speakers of English Editing Certificate	9197-Language certificate.pdf
Peer-review Report	9197-Peer review(s).pdf
Scientific Misconduct Check	9197-CrossCheck.jpg
Scientific Editor Work List	9197-Scientific editor work list.pdf