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6/21/2024 3:14:32 AM | Browse: 344 | Download: 979
Publication Name World Journal of Gastroenterology
Manuscript ID 92053
Country Italy
Received
2024-01-13 21:18
Peer-Review Started
2024-01-13 21:18
First Decision by Editorial Office Director
2024-04-08 19:50
Return for Revision
2024-04-08 19:50
Revised
2024-05-04 16:53
Publication Fee Transferred
Second Decision by Editor
2024-05-27 02:41
Second Decision by Editor-in-Chief
Final Decision by Editorial Office Director
2024-05-27 05:12
Articles in Press
2024-05-27 05:12
Edit the Manuscript by Language Editor
2024-06-02 19:53
Typeset the Manuscript
2024-06-11 06:45
Publish the Manuscript Online
2024-06-21 03:14
ISSN 1007-9327 (print) and 2219-2840 (online)
Open Access This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/
Copyright ©The Author(s) 2024. Published by Baishideng Publishing Group Inc. All rights reserved.
Article Reprints For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
Permissions For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
Publisher Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website http://www.wjgnet.com
Category Surgery
Manuscript Type Editorial
Article Title Relationship between mast cell, angiogenesis and pancreatic cancer: Our experience
Manuscript Source Invited Manuscript
All Author List Francesca Vescio, Michele Ammendola, Giuseppe Currò and Silvia Curcio
ORCID
Author(s) ORCID Number
Francesca Vescio http://orcid.org/0000-0002-0929-1671
Michele Ammendola http://orcid.org/0000-0001-8043-6100
Giuseppe Currò http://orcid.org/0000-0001-9566-1378
Funding Agency and Grant Number
Corresponding Author Michele Ammendola, N/A, Professor, Science of Health Department, Digestive Surgery Unit, University “Magna Graecia” Medical School, University Hospital “R. Dulbecco”, Viale Europa Loc Germaneto, Catanzaro 88100, Italy. michele.ammendola@libero.it
Key Words Mast cells; C-Kit receptor; Tryptase; Angiogenesis; Microvascular density; Endothelial area; Pancreatic tumour tissue; Adjacent normal tissue
Core Tip In this editorial we focus on the mechanisms linking pancreatic inflammation to pancreatic cancer. Pancreatic cancer remains one of the most aggressive pathologies. A better understanding of its etiology and identification of risk factors are essential for primary prevention. Mast cells contain proangiogenic factors, particularly tryptase, which are associated with increased angiogenesis. We evaluated the role of mast cells in angiogenesis in both pancreatic ductal adenocarcinoma tissue and adjacent normal tissue by assessing the density of c-Kit receptor-positive mast cells, the density of tryptase-positive mast cells, the area of tryptase-positive mast cells, and angiogenesis in terms of microvascularisation density.
Publish Date 2024-06-21 03:14
Citation

Vescio F, Ammendola M, Currò G, Curcio S. Relationship between mast cell, angiogenesis and pancreatic cancer: Our experience. World J Gastroenterol 2024; 30(23): 2927-2930

URL https://www.wjgnet.com/1007-9327/full/v30/i23/2927.htm
DOI https://dx.doi.org/10.3748/wjg.v30.i23.2927
Full Article (PDF) WJG-30-2927-with-cover.pdf