Publication Name	World Journal of Gastrointestinal Oncology
Manuscript ID	92098
Country	China

Received	2024-01-15 07:15
Peer-Review Started	2024-01-15 07:15
To Make the First Decision
Return for Revision	2024-02-05 20:31
Revised	2024-02-14 15:19
Second Decision	2024-03-28 01:51
Accepted by Journal Editor-in-Chief
Accepted by Executive Editor-in-Chief	2024-03-28 05:00
Articles in Press	2024-03-28 05:00
Publication Fee Transferred
Edit the Manuscript by Language Editor
Typeset the Manuscript	2024-04-22 04:33
Publish the Manuscript Online	2024-05-09 13:59

ISSN	1948-5204 (online)
Open Access	This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/
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Category	Gastroenterology & Hepatology
Manuscript Type	Retrospective Study
Article Title	Clinical outcome and prognostic factors of T4N0M0 colon cancer after R0 resection: A retrospective study
Manuscript Source	Unsolicited Manuscript
All Author List	Bang Liu, Zhao-Xiong Zhang, Xin-Yang Nie, Wei-Lin Sun, Yong-Jia Yan and Wei-Hua Fu
ORCID	Author(s) ORCID Number Bang Liu http://orcid.org/0000-0002-2637-0945 Yong-Jia Yan http://orcid.org/0000-0002-9496-2766 Wei-Hua Fu http://orcid.org/0000-0003-2576-865X
Funding Agency and Grant Number	Funding Agency Grant Number Health Science and Technology Project of Tianjin Health Commission ZC20190 Tianjin Key Medical Discipline (Specialty) Construction Project TJYXZDXK-005A Tianjin Medical University Clinical Research Fund 22ZYYLCCG04
Corresponding Author	Wei-Hua Fu, MD, PhD, Professor, Surgeon, Teacher, Department of General Surgery, Tianjin Medical University General Hospital, Tianjin Medical University, No. 154 Anshan Road, Tianjin 300052, China. tjmughgs_fwh@163.com
Key Words	T4N0M0 colon cancer; Prognosis; Multivariate analysis; Nomogram; Colon cancer
Core Tip	Paradoxically, patients with T4N0M0 (stage II, no lymph node metastasis) colon cancer have a worse prognosis than those with T2N1-2M0 (stage III). However, no previous report has addressed this issue. A total of 200 patients underwent radical surgery with pTNM “T4N0M0” were enrolled in this study. The clinical data and outcomes of the 200 patients were analyzed. We confirmed enterostomy, T stage, right hemicolon, irregular review, carbohydrate antigen 199 were independent risk factors of overall survival by using multivariate analysis. A nomogram model based on these factors was established to predict the prognosis of patients with T4N0M0 colon cancer.
Publish Date	2024-05-09 13:59
Citation	Liu B, Zhang ZX, Nie XY, Sun WL, Yan YJ, Fu WH. Clinical outcome and prognostic factors of T4N0M0 colon cancer after R0 resection: A retrospective study. World J Gastrointest Oncol 2024; 16(5): 1869-1877
URL	https://www.wjgnet.com/1948-5204/full/v16/i5/1869.htm
DOI	10.4251/wjgo.v16.i5.1869

Full Article (PDF)	WJGO-16-1869-with-cover.pdf
Manuscript File	92098_Auto_Edited-YJP.docx
Answering Reviewers	92098-Answering reviewers.pdf
Audio Core Tip	92098-Audio core tip.mp3
Biostatistics Review Certificate	92098-Biostatistics statement.pdf
Conflict-of-Interest Disclosure Form	92098-Conflict-of-interest statement.pdf
Copyright License Agreement	92098-Copyright license agreement.pdf
Approved Grant Application Form(s) or Funding Agency Copy of any Approval Document(s)	92098-Grant application form(s).pdf
Signed Informed Consent Form(s) or Document(s)	92098-Informed consent statement.pdf
Institutional Review Board Approval Form or Document	92098-Institutional review board statement.pdf
Non-Native Speakers of English Editing Certificate	92098-Language certificate.pdf
Peer-review Report	92098-Peer-review(s).pdf
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Scientific Editor Work List	92098-Scientific editor work list.pdf
CrossCheck Report	92098-CrossCheck.png
CrossCheck Report	92098-CrossCheck report.pdf