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Articles Published Processes
4/25/2024 5:24:44 AM | Browse: 14 | Download: 11
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Received |
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2024-01-17 12:31 |
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Peer-Review Started |
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2024-01-17 12:31 |
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To Make the First Decision |
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Return for Revision |
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2024-02-03 02:34 |
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2024-02-15 13:54 |
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Second Decision |
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2024-03-01 02:56 |
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Accepted by Journal Editor-in-Chief |
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Accepted by Company Editor-in-Chief |
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2024-03-01 06:24 |
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Articles in Press |
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2024-03-01 06:24 |
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Publication Fee Transferred |
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Edit the Manuscript by Language Editor |
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Typeset the Manuscript |
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2024-04-17 07:01 |
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Publish the Manuscript Online |
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2024-04-25 05:24 |
| ISSN |
1948-0210 (online) |
| Open Access |
This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/Licenses/by-nc/4.0/ |
| Copyright |
©The Author(s) 2024. Published by Baishideng Publishing Group Inc. All rights reserved. |
| Article Reprints |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
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| Permissions |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
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| Publisher |
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
| Website |
http://www.wjgnet.com |
| Category |
Cell & Tissue Engineering |
| Manuscript Type |
Editorial |
| Article Title |
Adipose-derived regenerative therapies for the treatment of knee osteoarthritis
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| Manuscript Source |
Invited Manuscript |
| All Author List |
Ilias E Epanomeritakis and Wasim S Khan |
| ORCID |
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| Funding Agency and Grant Number |
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| Corresponding Author |
Wasim S Khan, FRCS, MBChB, MSc, PhD, Associate Professor, Surgeon, Division of Trauma and Orthopaedic Surgery, Department of Surgery, University of Cambridge, Hills Road, Cambridge CB2 0QQ, United Kingdom. wk280@cam.ac.uk |
| Key Words |
Knee osteoarthritis; Mesenchymal stromal cells; Adipose tissue; Stromal vascular fraction; Micro-fragmented adipose tissue; Regeneration |
| Core Tip |
Adipose tissue products are becoming increasingly popular regenerative therapies for treating knee osteoarthritis. Encouraging results have been demonstrated in numerous observational studies and randomized trials. However, it is important to distinguish among isolated adipose-derived mesenchymal stromal cells (ASCs), stromal vascular fraction (SVF), and micro-fragmented adipose tissue (MFAT) to avoid study heterogeneity and improve the quality of evidence regarding these therapies. Different modes of preparation, cell composition, and physical properties are likely to influence the regenerative function of ASCs. To elucidate which adipose-derived therapy is superior for cartilage regeneration, randomized trials are needed to compare ASCs, SVF, and MFAT as distinct therapies. |
| Publish Date |
2024-04-25 05:24 |
| Citation |
Epanomeritakis IE, Khan WS. Adipose-derived regenerative therapies for the treatment of knee osteoarthritis. World J Stem Cells 2024; 16(4): 324-333 |
| URL |
https://www.wjgnet.com/1948-0210/full/v16/i4/324.htm |
| DOI |
https://dx.doi.org/10.4252/wjsc.v16.i4.324 |
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