ISSN |
1948-9358 (online) |
Open Access |
This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/ |
Copyright |
© The Author(s) 2024. Published by Baishideng Publishing Group Inc. All rights reserved. |
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Publisher |
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
Website |
http://www.wjgnet.com |
Category |
Endocrinology & Metabolism |
Manuscript Type |
Basic Study |
Article Title |
Growth hormone improves insulin resistance in visceral adipose tissue after duodenal-jejunal bypass by regulating adiponectin secretion
|
Manuscript Source |
Unsolicited Manuscript |
All Author List |
Zitian Liu, Guangwei Yang, Xiang Zhao, Shuo-Hui Dong, Yang Jiao, Zheng Ge, Ao Yu, Xiqiang Zhang, Xinzhen Xu, Zhiqiang Cheng, Xiang Zhang and Kexin Wang |
ORCID |
|
Funding Agency and Grant Number |
Funding Agency |
Grant Number |
National Natural Science Foundation of China (Key Program) |
82070852 |
National Natural Science Foundation of China (Key Program) |
82270901 |
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Corresponding Author |
Kexin Wang, Doctor, Doctor, Doctor, Department of general surgery, Qilu hospital of Shandong University, 107 Wenhua West Road, Jinan City, Jinan 250012, Shandong Province, China. wkx3726@163.com |
Key Words |
Growth hormone; Insulin resistance; Bariatric surgery; Adipose tissue; Adiponectin |
Core Tip |
Our results provide focused insight into the effects of duodenal-jejunal bypass (DJB) on adipose tissue function and insulin resistance in diabetic male rats. Unlike previous studies that often focused on broader metabolic improvements after DJB, this study focused on adipocytes and their molecular changes. Establishing a link between growth hormone (GH), adiponectin, and insulin sensitivity by identifying alterations in the GH pathway. |
Publish Date |
2024-06-11 14:35 |
Citation |
<p>Liu Z, Yang G, Zhao X, Dong SH, Jiao Y, Ge Z, Yu A, Zhang X, Xu X, Cheng Z, Zhang X, Wang K. Growth hormone improves insulin resistance in visceral adipose tissue after duodenal-jejunal bypass by regulating adiponectin secretion. <i>World J Diabetes</i> 2024; 15(6): 1340-1352</p> |
URL |
https://www.wjgnet.com/1948-9358/full/v15/i6/1340.htm |
DOI |
https://dx.doi.org/10.4239/wjd.v15.i6.1340 |