Publication Name	World Journal of Gastroenterology
Manuscript ID	9223
Country	China

Received	2014-01-27 12:05
Peer-Review Started	2014-01-27 14:19
To Make the First Decision	2014-03-13 18:58
Return for Revision	2014-03-20 08:07
Revised	2014-03-27 19:31
Second Decision	2014-05-05 09:34
Accepted by Journal Editor-in-Chief
Accepted by Executive Editor-in-Chief	2014-05-05 10:04
Articles in Press	2014-05-23 10:42
Publication Fee Transferred
Edit the Manuscript by Language Editor	2014-05-19 16:08
Typeset the Manuscript	2014-08-22 14:30
Publish the Manuscript Online	2014-09-07 13:31

ISSN	1007-9327 (print) and 2219-2840 (online)
Open Access
Copyright
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Website	http://www.wjgnet.com

Category	Surgery
Manuscript Type	Observational Study
Article Title	Low immediate postoperative platelet count is associated with hepatic insufficiency after hepatectomy
Manuscript Source	Unsolicited Manuscript
All Author List	Hai-Qing Wang, Jian Yang, Jia-Yin Yang, Wen-Tao Wang and Lu-Nan Yan
Funding Agency and Grant Number	Funding Agency Grant Number National Science and Technology Major Project of China 2012ZX10002-016 National Science and Technology Major Project of China 2012ZX10002-017
Corresponding Author	Lu-Nan Yan, MD, PhD, Department of Liver Surgery, Liver Transplantation Center, West China Hospital of Sichuan University, No. 37, Guo Xue Xiang, Chengdu 610041, Sichuan Province, China. yanlunan_688@163.com
Key Words	Thrombocytopenia; Hepatic insufficiency; Hepatocellular carcinoma; Hepatectomy; Hepatitis B
Core Tip	Recent animal experiments suggested that platelets not only have a role in hemostasis and thrombogenesis, but can also improve liver function by mediating liver regeneration. Our study found that patients with a low immediate postoperative platelet count < 100 × 109/L had more grade Ⅲ-Ⅴ complications, and higher rates of postoperative liver failure, hepatic insufficiency and mortality. In addition, these patients had worse liver function after liver resection, with higher alanine aminotransferase and bilirubin and lower albumin levels. This indicated that platelets could mediate liver regeneration in cirrhotic liver.
Publish Date	2014-09-07 13:31
Citation	Wang HQ, Yang J, Yang JY, Wang WT, Yan LN. Low immediate postoperative platelet count is associated with hepatic insufficiency after hepatectomy. World J Gastroenterol 2014; 20(33): 11871-11877
URL	http://www.wjgnet.com/1007-9327/full/v20/i33/11871.htm
DOI	http://dx.doi.org/10.3748/wjg.v20.i33.11871

Full Article (PDF)	WJG-20-11871.pdf
Full Article (Word)	WJG-20-11871.doc
Manuscript File	9223-Review.doc
Answering Reviewers	9223-Answering reviewers.pdf
Copyright License Agreement	9223-Copyright assignment.pdf
Non-Native Speakers of English Editing Certificate	9223-Language certificate.PDF
Peer-review Report	9223-Peer review.pdf
Scientific Editor Work List	9223-Scientific editor work list.pdf