Publication Name	World Journal of Gastroenterology
Manuscript ID	9231
Country	China

Received	2014-01-29 10:06
Peer-Review Started	2014-02-08 09:52
To Make the First Decision	2014-02-27 13:36
Return for Revision	2014-03-11 12:15
Revised	2014-05-02 23:11
Second Decision	2014-07-16 12:54
Accepted by Journal Editor-in-Chief
Accepted by Executive Editor-in-Chief	2014-07-16 13:05
Articles in Press	2014-07-16 17:53
Publication Fee Transferred
Edit the Manuscript by Language Editor	2014-10-24 23:28
Typeset the Manuscript	2014-11-11 16:56
Publish the Manuscript Online	2014-11-20 20:51

ISSN	1007-9327 (print) and 2219-2840 (online)
Open Access
Copyright
Article Reprints	For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
Permissions	For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
Publisher	Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website	http://www.wjgnet.com

Category	Gastroenterology & Hepatology
Manuscript Type	Retrospective Study
Article Title	Insulin-like growth factor receptor-1 overexpression is associated with poor response of rectal cancers to radiotherapy
Manuscript Source	Invited Manuscript
All Author List	Xiao-Yu Wu, Zhen-Feng Wu, Qin-Hong Cao, Che Chen, Zhi-Wei Chen, Zhe Xu, Wei-Su Li, Fu-Kun Liu, Xue-Quan Yao and Gang Li
Funding Agency and Grant Number	Funding Agency Grant Number National Natural Science Foundation of China 81402523 (to Wu XY) National Natural Science Foundation of China 81201797 (to Li G)
Corresponding Author	Gang Li, MD, Department of General Surgery, Jiangsu Cancer Hospital, Affiliated Cancer Hospital of Nanjing Medical University, 42 Baiziting, Nanjing 210009, Jiangsu Province, China. searain@sohu.com
Key Words	Insulin-like growth factor-1 receptor; Rectal carcinoma; Preoperative radiotherapy; Immunohistochemistry; Reverse transcription-polymerase chain reaction
Core Tip	This was the first report examining the relation between IGF-1R expression and radiosensitivity in rectal cancer. Results showed that IGF-1R hyperexpression is significantly associated with poor response to radiotherapy. Compared with the preradiation biopsy specimens, the paired post-operative specimens showed a significantly increased IGF-1R expression in the residual cancer cells.
Publish Date	2014-11-20 20:51
Citation	Wu XY, Wu ZF, Cao QH, Chen C, Chen ZW, Xu Z, Li WS, Liu FK, Yao XQ, Li G. Insulin-like growth factor receptor-1 overexpression is associated with poor response of rectal cancers to radiotherapy. World J Gastroenterol 2014; 20(43): 16268-16274
URL	http://www.wjgnet.com/1007-9327/full/v20/i43/16268.htm
DOI	http://dx.doi.org/10.3748/wjg.v20.i43.16268

Full Article (PDF)	WJG-20-16268.pdf
Full Article (Word)	WJG-20-16268.doc
Manuscript File	9231-Review.doc
Answering Reviewers	9231-Answering reviewers.pdf
Copyright License Agreement	9231-Copyright assignment.pdf
Non-Native Speakers of English Editing Certificate	9231-Language certificate.pdf
Peer-review Report	9231-Peer reviews.pdf
Scientific Misconduct Check	9231-CrossCheck.jpg
Scientific Editor Work List	9231-Scientific editor work list.pdf