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6/20/2024 3:42:22 AM | Browse: 192 | Download: 421
Publication Name World Journal of Hepatology
Manuscript ID 92330
Country China
Received
2024-01-23 10:08
Peer-Review Started
2024-01-23 10:08
First Decision by Editorial Office Director
2024-03-12 04:24
Return for Revision
2024-03-12 04:24
Revised
2024-04-08 02:09
Publication Fee Transferred
Second Decision by Editor
2024-04-28 02:37
Second Decision by Editor-in-Chief
Final Decision by Editorial Office Director
2024-04-28 08:01
Articles in Press
2024-04-28 08:01
Edit the Manuscript by Language Editor
Typeset the Manuscript
2024-06-13 01:16
Publish the Manuscript Online
2024-06-20 03:42
ISSN 1948-5182 (online)
Open Access This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/Licenses/by-nc/4.0/
Copyright © The Author(s) 2024. Published by Baishideng Publishing Group Inc. All rights reserved.
Article Reprints For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
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Publisher Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website http://www.wjgnet.com
Category Medicine, Research & Experimental
Manuscript Type Basic Study
Article Title Diagnostic and prognostic role of LINC01767 in hepatocellular carcinoma
Manuscript Source Unsolicited Manuscript
All Author List Li Zhang, Tong-Xing Cui, Xiang-Zhi Li, Chong Liu and Wen-Qin Wang
ORCID
Author(s) ORCID Number
Wen-Qin Wang http://orcid.org/0000-0003-3346-316X
Funding Agency and Grant Number
Funding Agency Grant Number
Foundation of Qingdao Postdoctoral Innovation Project QDBSH20230101019
Funded State Key Laboratory of Marine Food Processing & Safety Control, Qingdao SKL2023M05
Corresponding Author Wen-Qin Wang, MMed, Postdoc, Researcher, School of Life Sciences, Shandong University (Qingdao), No. 72 of Binhai Road, Jimo District, Qingdao 26637, Shandong Province, China. wenqinwangsdu@163.com
Key Words Clone formation; Cell proliferation; GSE243371; Multi-omics analysis; LINC01767; Hepatocellular carcinoma
Core Tip LINC01767 was down-regulated based on The Cancer Genome Atlas and GSE dataset. It was positively with the cancer stemness in hepatocellular carcinoma (HCC) based on the single cell sequence data. LINC01767 demonstrate a good diagnostic and diagnostic performance. The 9-gene model demonstrated better performance than the 5-gene model in predicting the overall survival of HCC patients using least absolute shrinkage and selection operator regression, with an area under the curve greater than 0.75. LINC01767 was down regulated obviously in tumor than para-tumor tissues in our cohort. LINC01767 was down regulated in cancer cell line comparing with LO2; the over expression of LINC01767 inhibit the cell proliferation and imped the clone formation of Huh7 in vitro.
Publish Date 2024-06-20 03:42
Citation

Zhang L, Cui TX, Li XZ, Liu C, Wang WQ. Diagnostic and prognostic role of LINC01767 in hepatocellular carcinoma. World J Hepatol 2024; 16(6): 932-950

URL https://www.wjgnet.com/1948-5182/full/v16/i6/932.htm
DOI https://dx.doi.org/10.4254/wjh.v16.i6.932
Full Article (PDF) WJH-16-932-with-cover.pdf
Manuscript File 92330_Auto_Edited-YJP.docx
Answering Reviewers 92330-answering-reviewers.pdf
Audio Core Tip 92330-audio.mp3
Biostatistics Review Certificate 92330-biostatistics-statement.pdf
Conflict-of-Interest Disclosure Form 92330-conflict-of-interest-statement.pdf
Copyright License Agreement 92330-copyright-assignment.pdf
Institutional Review Board Approval Form or Document 92330-institutional-review-board-statement.pdf
Non-Native Speakers of English Editing Certificate 92330-non-native-speakers.pdf
Supplementary Material 92330-supplementary-material.pdf
Peer-review Report 92330-peer-reviews.pdf
Scientific Misconduct Check 92330-scientific-misconduct-check.png
Scientific Editor Work List 92330-scientific-editor-work-list.pdf
CrossCheck Report 92330-crosscheck-report.pdf