Publication Name	World Journal of Otorhinolaryngology
Manuscript ID	92333
Country	Russia

Received	2024-02-23 10:40
Peer-Review Started	2024-02-23 10:40
To Make the First Decision
Return for Revision	2024-08-26 06:27
Revised	2024-09-19 15:42
Second Decision	2024-10-28 02:37
Accepted by Journal Editor-in-Chief
Accepted by Executive Editor-in-Chief	2024-10-28 10:57
Articles in Press	2024-10-28 10:57
Publication Fee Transferred	2024-10-30 20:10
Edit the Manuscript by Language Editor	2024-11-14 01:46
Typeset the Manuscript	2024-11-26 01:24
Publish the Manuscript Online	2024-11-28 07:00

ISSN	2218-6247 (online)
Open Access	This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/
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Category	Oncology
Manuscript Type	Retrospective Study
Article Title	Recurrent oropharyngeal cancer: Analysis of surgical treatment outcomes
Manuscript Source	Unsolicited Manuscript
All Author List	Konstantin Ilkaev, Shalva R Gvetadze, Ekaterina A Roshchina, Ruben I Azizyan, Ali M Mudunov, Mikhail V Bolotin, Xin Yang and Denis Larinov
ORCID	Author(s) ORCID Number Konstantin Ilkaev http://orcid.org/0000-0002-6225-663X Shalva R Gvetadze http://orcid.org/0000-0003-3806-9022 Ekaterina A Roshchina http://orcid.org/0000-0003-0452-9430 Ruben I Azizyan http://orcid.org/0000-0002-4046-1894 Ali M Mudunov http://orcid.org/0000-0002-0918-3857 Mikhail V Bolotin http://orcid.org/0000-0001-7534-6565 Xin Yang http://orcid.org/0000-0003-2626-9094 Denis Larinov http://orcid.org/0009-0009-9749-0192
Funding Agency and Grant Number
Corresponding Author	Konstantin Ilkaev, MD, PhD, Head and Neck Cancer Surgery and Oncology Department, NN Blokhin National Medical Research Center of Oncology, No. 23 Kashirskoye Highway, Moscow 115478, Moskva, Russia. dr.ilkaev@gmail.com
Key Words	Oropharyngeal cancer; Transoral laser resection; Open surgery; Recurrent tumor; Oropharyngeal squamous cell carcinoma
Core Tip	Our study included a large retrospective part and two prospective compare groups of patients, who were subjected to open surgery or transoral robotic surgery and laser resection (TLR). The results show that in properly elected patients TLR is not just reasonable but has a tendency to be a favorable alternative for recurrent oropharyngeal cancer compared to the outcomes of open surgery group. TLR in our study was associated with shorter operating time, lower blood loss counts and postoperative complications rate, higher quality of life and proportionate 2-year survival when compared with open surgery performance rates. As open surgery was for decades the mainstream treatment approach for recurrent tumors of the oropharyngeal zone considerable experience is accumulated, which indicates that this management bears unfavorable functional outcomes. The results of our comparative study defined higher quality of life in patients who underwent TLR.
Publish Date	2024-11-28 07:00
Citation	<p>Ilkaev K, Gvetadze SR, Roshchina EA, Azizyan RI, Mudunov AM, Bolotin MV, Yang X, Larinov D. Recurrent oropharyngeal cancer: Analysis of surgical treatment outcomes. <i>World J Otorhinolaryngol</i> 2024; 11(3): 25-32</p>
URL	https://www.wjgnet.com/2218-6247/full/v11/i3/25.htm
DOI	https://dx.doi.org/10.5319/wjo.v11.i3.25

Full Article (PDF)	WJO-11-25-with-cover.pdf
Manuscript File	92333_Auto_Edited_030725.docx
Answering Reviewers	92333-answering-reviewers.pdf
Audio Core Tip	92333-audio.m4a
Biostatistics Review Certificate	92333-biostatistics-statement.pdf
Conflict-of-Interest Disclosure Form	92333-conflict-of-interest-statement.pdf
Copyright License Agreement	92333-copyright-assignment.pdf
Signed Informed Consent Form(s) or Document(s)	92333-informed-consent-statement.pdf
Institutional Review Board Approval Form or Document	92333-institutional-review-board-statement.pdf
Non-Native Speakers of English Editing Certificate	92333-non-native-speakers.pdf
Peer-review Report	92333-peer-reviews.pdf
Scientific Misconduct Check	92333-scientific-misconduct-check.png
Scientific Editor Work List	92333-scientific-editor-work-list.pdf
CrossCheck Report	92333-crosscheck-report.pdf