Publication Name	World Journal of Gastrointestinal Surgery
Manuscript ID	92347
Country	China

Received	2024-02-22 01:43
Peer-Review Started	2024-02-22 01:44
To Make the First Decision
Return for Revision	2024-04-03 05:43
Revised	2024-04-11 09:59
Second Decision	2024-04-12 02:33
Accepted by Journal Editor-in-Chief
Accepted by Executive Editor-in-Chief	2024-04-12 05:19
Articles in Press	2024-04-12 05:19
Publication Fee Transferred
Edit the Manuscript by Language Editor
Typeset the Manuscript	2024-05-14 07:41
Publish the Manuscript Online	2024-05-23 09:40

ISSN	1948-9366 (online)
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Category	Gastroenterology & Hepatology
Manuscript Type	Retrospective Study
Article Title	GLI1 and PTTG1 expression in colorectal carcinoma patients undergoing radical surgery and their correlation with lymph node metastasis
Manuscript Source	Unsolicited Manuscript
All Author List	Feng Cao, Yang-Yan Chen and Hong-Cheng Wang
ORCID	Author(s) ORCID Number Feng Cao http://orcid.org/0009-0008-1418-5997
Funding Agency and Grant Number
Corresponding Author	Feng Cao, MM, Doctor, Doctor, Department of Care Section, Beijing Geriatric Hospital, No. 118 Wenquan Road, Wenquan Town, Haidian District, Beijing 100095, China. caofengbj@163.com
Key Words	Lymph node metastasis; Radical resection; PTTG1; GLI1; Colorectal carcinoma
Core Tip	The main goal of radical surgery for colorectal carcinoma (CRC) is to completely remove the primary tumor and regional lymph nodes. Lymph nodes are essential in predicting patient prognosis and for determining the need for adjuvant chemotherapy after surgical resection. In this study, the expression of GLI1 and PTTG1 in patients with CRC undergoing radical surgery and their correlation with lymph node metastasis (LNM) were examined. Aberrant overexpression of GLI1 and PTTG1 was confirmed in patients undergoing radical surgery for CRC. In addition, both GLI1 and PTTG1 were significantly related to LNM and could be used as predictors of LNM, indicating their clinical significance in the evaluation of CRC cases and the development of treatment plans.
Publish Date	2024-05-23 09:40
Citation	<p>Cao F, Chen YY, Wang HC. GLI1 and PTTG1 expression in colorectal carcinoma patients undergoing radical surgery and their correlation with lymph node metastasis. <i>World J Gastrointest Surg</i> 2024; 16(5): 1328-1335</p>
URL	https://www.wjgnet.com/1948-9366/full/v16/i5/1328.htm
DOI	https://dx.doi.org/10.4240/wjgs.v16.i5.1328

Full Article (PDF)	WJGS-16-1328-with-cover.pdf
Manuscript File	92347_Auto_Edited-YJP.docx
Answering Reviewers	92347-Answering reviewers.pdf
Audio Core Tip	92347-Audio core tip.mp3
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