Publication Name	World Journal of Clinical Cases
Manuscript ID	92348
Country	China

Received	2024-01-24 00:52
Peer-Review Started	2024-01-24 00:52
To Make the First Decision
Return for Revision	2024-02-08 03:56
Revised	2024-02-21 11:43
Second Decision	2024-03-01 02:56
Accepted by Journal Editor-in-Chief
Accepted by Executive Editor-in-Chief	2024-03-01 08:11
Articles in Press	2024-03-01 08:11
Publication Fee Transferred
Edit the Manuscript by Language Editor
Typeset the Manuscript	2024-03-18 06:52
Publish the Manuscript Online	2024-03-25 08:14

ISSN	2307-8960 (online)
Open Access	This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
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Category	Cardiac & Cardiovascular Systems
Manuscript Type	Case Report
Article Title	Challenging anticoagulation therapy for multiple primary malignant tumors combined with thrombosis: A case report and review of literature
Manuscript Source	Unsolicited Manuscript
All Author List	Jia-Xin Chen, Ling-Ling Xu, Jing-Ping Cheng and Xun-Hua Xu
ORCID	Author(s) ORCID Number Jia-Xin Chen http://orcid.org/0009-0005-5419-7229 Ling-Ling Xu http://orcid.org/0009-0005-1047-0246 Jing-Ping Cheng http://orcid.org/0009-0005-2251-6977 Xun-Hua Xu http://orcid.org/0000-0002-8364-1393
Funding Agency and Grant Number
Corresponding Author	Jing-Ping Cheng, Doctor, DPhil, Chief Doctor, China Resources Wisco General Hospital, China Resources Wisco General Hospital, No. 29 Metallurgical Avenue, Qingshan District, Wuhan 430080, Hubei Province, China. 404178516@qq.com
Key Words	Venous thromboembolism; Cancer-associated thrombosis; Anticoagulation therapy; iliac vein compression syndrome; COVID-19; Thrombocytopenia; Case report
Core Tip	Lung cancer and pancreatic cancer form a rare combination of multiple primary malignant tumors. This patient had a rare lower extremity venous thrombosis complicated by pulmonary embolism. Its causes included a history of various malignant tumors, recent novel coronavirus infection, insufficient anticoagulant therapy for previous lower extremity thrombosis, and iliac vein compression syndrome. Anticoagulant therapy poses challenges to patients with active cancer and reduced fibrinogen levels; abnormally elevated D-dimer levels; and decreased platelet counts. This article provides a comprehensive overview of the therapeutic options for anticoagulation.
Publish Date	2024-03-25 08:14
Citation	Chen JX, Xu LL, Cheng JP, Xu XH. Challenging anticoagulation therapy for multiple primary malignant tumors combined with thrombosis: A case report and review of literature. World J Clin Cases 2024; 12(9): 1704-1711
URL	https://www.wjgnet.com/2307-8960/full/v12/i9/1704.htm
DOI	https://dx.doi.org/10.12998/wjcc.v12.i9.1704

Full Article (PDF)	WJCC-12-1704-with-cover.pdf
CARE Checklist–2016	92348-CARE Checklist (2016).pdf
Manuscript File	92348_Auto_Edited-LJH-YJP.docx
Answering Reviewers	92348-Answering reviewers.pdf
Audio Core Tip	92348-Audio core tip.m4a
Conflict-of-Interest Disclosure Form	92348-Conflict-of-interest statement.pdf
Copyright License Agreement	92348-Copyright license agreement.pdf
Signed Consent for Treatment Form(s) or Document(s)	92348-Informed consent statement.pdf
Non-Native Speakers of English Editing Certificate	92348-Language certificate.pdf
Peer-review Report	92348-Peer-review(s).pdf
Scientific Misconduct Check	92348-Bing-Liu JH-2.png
Scientific Misconduct Check	92348-CrossCheck.png
Scientific Editor Work List	92348-Scientific editor work list.pdf
CrossCheck Report	92348-CrossCheck report.pdf