Publication Name	World Journal of Stem Cells
Manuscript ID	92457
Country	China

Received	2024-01-26 10:28
Peer-Review Started	2024-01-26 10:28
To Make the First Decision
Return for Revision	2024-03-12 03:53
Revised	2024-03-17 15:10
Second Decision	2024-04-15 10:04
Accepted by Journal Editor-in-Chief	2024-04-18 05:02
Accepted by Executive Editor-in-Chief	2024-04-19 06:35
Articles in Press	2024-04-19 06:35
Publication Fee Transferred
Edit the Manuscript by Language Editor
Typeset the Manuscript	2024-06-15 09:38
Publish the Manuscript Online	2024-06-25 10:11

ISSN	1948-0210 (online)
Open Access	This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/Licenses/by-nc/4.0/
Copyright	© The Author(s) 2024. Published by Baishideng Publishing Group Inc. All rights reserved.
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Category	Gastroenterology & Hepatology
Manuscript Type	Basic Study
Article Title	Umbilical cord mesenchymal stem cell exosomes alleviate necrotizing enterocolitis in neonatal mice by regulating intestinal epithelial cells autophagy
Manuscript Source	Unsolicited Manuscript
All Author List	Lin Zhu, Lu He, Wu Duan, Bo Yang and Ning Li
ORCID	Author(s) ORCID Number Wu Duan http://orcid.org/0009-0006-5696-1013 Bo Yang http://orcid.org/0000-0002-3183-5567 Ning Li http://orcid.org/0000-0002-4142-0656
Funding Agency and Grant Number	Funding Agency Grant Number China International Medical Foundation Z-2019-41-2101-04 China Postdoctoral Science Foundation Funded Project 2022M721957 West China Psychiatric Association WL2022102 Guangdong Basic and Applied Basic Research Foundation 2023A1515110717
Corresponding Author	Ning Li, Doctor, Doctor, Doctor, Department of Physical Education, Heze University, No. 2269 Daxue Road, Mudan District, Heze 274015, Shandong Province, China. hzlqlm@163.com
Key Words	Necrotizing enterocolitis; Autophagy; Umbilical cord mesenchymal stem cell; Exosomes; Intestinal epithelial cell; Intestinal barrier function
Core Tip	Based on observations of clinical samples, this study revealed a new mechanism by which human umbilical cord mesenchymal stem cells-derived exosomes reduce the inflammatory response and intestinal barrier dysfunction in neonatal mice with necrotizing enterocolitis (NEC) from the perspective of intestinal epithelial cell autophagy. These findings offer new insights for the clinical application of exosomes in NEC treatment and contribute to the establishment of a solid theoretical foundation.
Publish Date	2024-06-25 10:11
Citation	<p>Zhu L, He L, Duan W, Yang B, Li N. Umbilical cord mesenchymal stem cell exosomes alleviate necrotizing enterocolitis in neonatal mice by regulating intestinal epithelial cells autophagy. <i>World J Stem Cells</i> 2024; 16(6): 728-738</p>
URL	https://www.wjgnet.com/1948-0210/full/v16/i6/728.htm
DOI	https://dx.doi.org/10.4252/wjsc.v16.i6.728

Full Article (PDF)	WJSC-16-728-with-cover.pdf
The ARRIVE Guidelines	92457-The-ARRIVE-Guidelines.pdf
Manuscript File	92457_Auto_Edited-YJP.docx
Answering Reviewers	92457-answering-reviewers.pdf
Audio Core Tip	92457-audio.mp3
Biostatistics Review Certificate	92457-biostatistics-statement.pdf
Conflict-of-Interest Disclosure Form	92457-conflict-of-interest-statement.pdf
Copyright License Agreement	92457-copyright-assignment.pdf
Approved Grant Application Form(s) or Funding Agency Copy of any Approval Document(s)	92457-foundation-statement.pdf
Institutional Animal Care and Use Committee Approval Form or Document	92457-institutional-animal-care-and-use-committee-statement.pdf
Institutional Review Board Approval Form or Document	92457-institutional-review-board-statement.pdf
Non-Native Speakers of English Editing Certificate	92457-non-native-speakers.pdf
Peer-review Report	92457-peer-reviews.pdf
Journal Editor-in-Chief Review Report	92457-journal-editor-in-chief.pdf
Scientific Misconduct Check	92457-scientific-misconduct-check.png
Scientific Editor Work List	92457-scientific-editor-work-list.pdf
CrossCheck Report	92457-crosscheck-report.pdf