Publication Name	World Journal of Gastroenterology
Manuscript ID	92476
Country	United States

Received	2024-01-26 23:30
Peer-Review Started	2024-01-26 23:30
To Make the First Decision
Return for Revision	2024-04-07 19:59
Revised	2024-04-07 22:40
Second Decision	2024-04-30 02:33
Accepted by Journal Editor-in-Chief
Accepted by Executive Editor-in-Chief	2024-04-30 10:05
Articles in Press	2024-04-30 10:05
Publication Fee Transferred
Edit the Manuscript by Language Editor
Typeset the Manuscript	2024-05-27 15:42
Publish the Manuscript Online	2024-05-27 09:35

ISSN	1007-9327 (print) and 2219-2840 (online)
Open Access	This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/Licenses/by-nc/4.0/
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Category	Gastroenterology & Hepatology
Manuscript Type	Letter to the Editor
Article Title	Downstaging strategies for unresectable hepatocellular carcinoma
Manuscript Source	Invited Manuscript
All Author List	Georgia Sofia Karachaliou, Nikolaos Dimitrokallis and Dimitrios P Moris
ORCID	Author(s) ORCID Number Georgia Sofia Karachaliou http://orcid.org/0000-0003-4091-3798 Dimitrios P Moris http://orcid.org/0000-0002-5276-0699
Funding Agency and Grant Number
Corresponding Author	Dimitrios P Moris, MD, MSc, PhD, Surgeon, Department of Surgery, Duke University Medical Center, 2301 Erwin Road, Durham, NC 27710, United States. dimmoris@yahoo.com
Key Words	Unresectable hepatocellular carcinoma; Hepatic arterial infusion chemotherapy; Downstaging; Hepatocellular carcinoma
Core Tip	Patients with hepatocellular carcinoma who undergo successful conversion therapy followed by curative-intent surgery may achieve a significant survival benefit compared to those who receive chemotherapy only without surgery. Hepatic artery infusion chemotherapy can be a potential downstaging strategy, since recent studies have demonstrated excellent outcomes in patients with colorectal liver metastatic disease as well as primary liver malignancies.
Publish Date	2024-05-27 09:35
Citation	<p>Karachaliou GS, Dimitrokallis N, Moris DP. Downstaging strategies for unresectable hepatocellular carcinoma. <i>World J Gastroenterol</i> 2024; 30(20): 2731-2733</p>
URL	https://www.wjgnet.com/1007-9327/full/v30/i20/2731.htm
DOI	https://dx.doi.org/10.3748/wjg.v30.i20.2731

Full Article (PDF)	WJG-30-2731-with-cover.pdf
Manuscript File	92476_Auto_Edited-JLW.docx
Answering Reviewers	92476-Answering reviewers.pdf
Audio Core Tip	92476-Audio core tip.m4a
Conflict-of-Interest Disclosure Form	92476-Conflict-of-interest statement.pdf
Copyright License Agreement	92476-Copyright license agreement.pdf
Peer-review Report	92476-Peer-review(s).pdf
Scientific Misconduct Check	92476-Bing-Wang JJ-2.png
Scientific Editor Work List	92476-Scientific editor work list.pdf
CrossCheck Report	92476-CrossCheck report.pdf