ISSN |
1948-5182 (online) |
Open Access |
This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/ |
Copyright |
© The Author(s) 2024. Published by Baishideng Publishing Group Inc. All rights reserved. |
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Publisher |
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
Website |
http://www.wjgnet.com |
Category |
Transplantation |
Manuscript Type |
Minireviews |
Article Title |
Immune remodulation in pediatric inherited metabolic liver diseases
|
Manuscript Source |
Invited Manuscript |
All Author List |
Yi-Chi Wu, Xue-Lin Xiang, June-Kong Yong, Meng Li, Lin-Man Li, Zi-Cheng Lv, Yi Zhou, Xi-Cheng Sun, Zi-Jie Zhang, Huan Tong, Xiao-Ying He, Qiang Xia and Hao Feng |
ORCID |
|
Funding Agency and Grant Number |
Funding Agency |
Grant Number |
Shanghai Science and Technology Development Foundation (Outstanding academic leader) |
23XD1423100 |
National Natural Science Foundation |
82241221 and 92059205 |
|
Corresponding Author |
Hao Feng, MD, PhD, Research Scientist, Surgeon, Department of Liver Surgery, Renji Hospital Affiliated to Shanghai Jiao Tong University, Shanghai Institute of Transplantation, Shanghai Engineering Research Center of Transplantation and Immunology, No. 160 Pujian Road, Shanghai 200127, China. surgeonfeng@live.com |
Key Words |
Liver transplantation; Inherited metabolic liver diseases; Immune microenvironment; Genetic metabolic liver diseases; Immunotherapy |
Core Tip |
It remains unclear whether concurrent infections are connected to immunological changes beyond the established metabolic imbalances in inherited metabolic liver diseases. Previous studies often focused on changes in liver parenchyma cells, but recent studies have shown that inherited hepatic metabolic diseases also have a profound impact on the liver's immune microenvironment. |
Publish Date |
2024-09-23 10:30 |
Citation |
<p>Wu YC, Xiang XL, Yong JK, Li M, Li LM, Lv ZC, Zhou Y, Sun XC, Zhang ZJ, Tong H, He XY, Xia Q, Feng H. Immune remodulation in pediatric inherited metabolic liver diseases. <i>World J Hepatol</i> 2024; 16(9): 1258-1268</p> |
URL |
https://www.wjgnet.com/1948-5182/full/v16/i9/1258.htm |
DOI |
https://dx.doi.org/10.4254/wjh.v16.i9.1258 |