BPG is committed to discovery and dissemination of knowledge
Articles Published Processes
5/14/2024 8:48:08 AM | Browse: 104 | Download: 577
 |
Received |
|
2024-01-30 12:48 |
|
Peer-Review Started |
|
2024-01-30 12:48 |
|
First Decision by Editorial Office Director |
|
2024-02-07 06:14 |
|
Return for Revision |
|
2024-02-07 06:14 |
|
Revised |
|
2024-02-14 18:17 |
 |
Publication Fee Transferred |
|
|
|
Second Decision by Editor |
|
2024-04-07 01:08 |
|
Second Decision by Editor-in-Chief |
|
|
|
Final Decision by Editorial Office Director |
|
2024-04-07 06:08 |
|
Articles in Press |
|
2024-04-07 06:08 |
|
Edit the Manuscript by Language Editor |
|
|
|
Typeset the Manuscript |
|
2024-05-08 06:57 |
|
Publish the Manuscript Online |
|
2024-05-14 08:48 |
| ISSN |
2307-8960 (online) |
| Open Access |
This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/licenses/by-nc/4.0/ |
| Copyright |
© The Author(s) 2024. Published by Baishideng Publishing Group Inc. All rights reserved. |
| Article Reprints |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
|
| Permissions |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
|
| Publisher |
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
| Website |
http://www.wjgnet.com |
| Category |
Genetics & Heredity |
| Manuscript Type |
Case Report |
| Article Title |
Role of savolitinib in advanced gastric adenocarcinoma with meningeal carcinomatosis and cerebellar metastasis: A case report
|
| Manuscript Source |
Unsolicited Manuscript |
| All Author List |
Zhi-Yun Weng, Wen-Ye Huang, Bin-Kan Shi and Jian-Jia Pan |
| ORCID |
|
| Funding Agency and Grant Number |
|
| Corresponding Author |
Zhi-Yun Weng, PhD, Chief Doctor, Department of Hematology, The Affiliated Yueqing Hospital of Wenzhou Medical University, No. 338 Qingyuan Road, Yueqing 325600, Zhejiang Province, China. weng_zhi_yun@163.com |
| Key Words |
Cellular-mesenchymal epithelial transition factor receptor; Savolitinib; Meningeal carcinomatosis; Gastric adenocarcinoma; Case report |
| Core Tip |
Common metastatic sites for gastric adenocarcinoma (GaC) occur in the lymph nodes, liver, and lungs. Additionally, brain metastases (BM) are rare. Interestingly, mesenchymal epithelial transition factor receptor (MET) amplification in GaC is rare, and its role in tumor metastasis remains unclear. Several previous reports have described the association between MET amplification and BM with GaC. This case highlights the unique phenomenon of rapid BM in advanced GaC after first-line treatment and the rapid short-term reduction of cerebellar metastases after the use of savolitinib. Therefore, it is hypothesized that MET amplification may be a key driver of BMs in GaC. |
| Publish Date |
2024-05-14 08:48 |
| Citation |
Weng ZY, Huang WY, Shi BK, Pan JJ. Role of savolitinib in advanced gastric adenocarcinoma with meningeal carcinomatosis and cerebellar metastasis: A case report. World J Clin Cases 2024; 12(15): 2636-2641 |
| URL |
https://www.wjgnet.com/2307-8960/full/v12/i15/2636.htm |
| DOI |
https://dx.doi.org/10.12998/wjcc.v12.i15.2636 |
© 2004-2026 Baishideng Publishing Group Inc. All rights reserved. 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
California Corporate Number: 3537345
