| ISSN |
1948-5204 (online) |
| Open Access |
This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/licenses/by-nc/4.0/ |
| Copyright |
© The Author(s) 2024. Published by Baishideng Publishing Group Inc. All rights reserved. |
| Article Reprints |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
|
| Permissions |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
|
| Publisher |
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
| Website |
http://www.wjgnet.com |
| Category |
Oncology |
| Manuscript Type |
Retrospective Study |
| Article Title |
Association between Helicobacter pylori infection, mismatch repair, HER2 and tumor-infiltrating lymphocytes in gastric cancer
|
| Manuscript Source |
Unsolicited Manuscript |
| All Author List |
Carlos A Castaneda, Miluska Castillo, Luis A Bernabe, Joselyn Sanchez, Matteo Fassan, Katherine Tello, Ignacio Ivan Wistuba, Ivan Chavez Passiuri, Eloy Ruiz, Juvenal Sanchez, Fernando Barreda, Daniel Valdivia, Yaqueline Bazan, Milagros Abad-Licham, Claudio Mengoa, Hugo Fuentes, Paola Montenegro, Ebert Poquioma, Raul Alatrista, Claudio J Flores and Luis Taxa |
| ORCID |
|
| Funding Agency and Grant Number |
| Funding Agency |
Grant Number |
| Ministerio de la Produccion de Peru |
317-PNICP-EC-2014 |
| Ministerio de la Produccion de Peru |
430-PNICP-PIAP-2014 |
| Consejo Nacional de Ciencia Tecnologia e Innovacion Tecnologica |
196-2015-FONDECYT |
| Consejo Nacional de Ciencia Tecnologia e Innovacion Tecnologica |
197-2015-FONDECYT |
| Consejo Nacional de Ciencia Tecnologia e Innovacion Tecnologica |
204-2015-FONDECYT |
|
| Corresponding Author |
Carlos A Castaneda, MD, MSc, Assistant Professor, Faculty of Health Sciences, Universidad Cientifica del Sur, Panamericana Sur 19, Villa El Salvador, Lima 15038, Peru. ccastaneda@gecoperu.org |
| Key Words |
Lymphocytes; Macrophages; Gastric cancer; Helicobacter pylori; HER2; Mismatch repair |
| Core Tip |
Absence of Helicobacter pylori was associated with high tumor-infiltrating lymphocyte (TIL) levels and CD8 density. Deficient mismatch-repair was associated with high TIL levels, and CD3 and CD8 density. Longer overall survival was associated with a low CD8/CD3 ratio, and high CD3 and CD3/CD163 ratio. |
| Publish Date |
2024-06-15 02:49 |
| Citation |
<p>Castaneda CA, Castillo M, Bernabe LA, Sanchez J, Fassan M, Tello K, Wistuba II, Chavez Passiuri I, Ruiz E, Sanchez J, Barreda F, Valdivia D, Bazan Y, Abad-Licham M, Mengoa C, Fuentes H, Montenegro P, Poquioma E, Alatrista R, Flores CJ, Taxa L. Association between Helicobacter pylori infection, mismatch repair, HER2 and tumor-infiltrating lymphocytes in gastric cancer. <i>World J Gastrointest Oncol</i> 2024; 16(6): 2487-2503</p> |
| URL |
https://www.wjgnet.com/1948-5204/full/v16/i6/2487.htm |
| DOI |
https://dx.doi.org/10.4251/wjgo.v16.i6.2487 |
