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6/15/2024 2:49:03 AM | Browse: 100 | Download: 382
Publication Name World Journal of Gastrointestinal Oncology
Manuscript ID 92561
Country China
Received
2024-01-29 17:10
Peer-Review Started
2024-01-29 17:10
To Make the First Decision
Return for Revision
2024-02-28 20:23
Revised
2024-03-12 13:20
Second Decision
2024-04-12 02:33
Accepted by Journal Editor-in-Chief
Accepted by Executive Editor-in-Chief
2024-04-12 05:34
Articles in Press
2024-04-12 05:34
Publication Fee Transferred
Edit the Manuscript by Language Editor
Typeset the Manuscript
2024-05-14 12:41
Publish the Manuscript Online
2024-06-15 02:49
ISSN 1948-5204 (online)
Open Access This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/
Copyright ©The Author(s) 2024. Published by Baishideng Publishing Group Inc. All rights reserved.
Article Reprints For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
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Publisher Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website http://www.wjgnet.com
Category Medical Laboratory Technology
Manuscript Type Basic Study
Article Title Circ_0004592: An auxiliary diagnostic biomarker for gastric cancer
Manuscript Source Unsolicited Manuscript
All Author List Shan Kong, Yan-Hua Xu, Ming Zheng, Shao-Qing Ju and Heng-Chuan Shi
ORCID
Author(s) ORCID Number
Shao-Qing Ju http://orcid.org/0009-0006-9764-5455
Funding Agency and Grant Number
Funding Agency Grant Number
Jiangsu Province Laboratory Medical Research Special Fund Project No. SYH-3201160-0061(2023008)
Corresponding Author Shao-Qing Ju, DPhil, Professor, Department of Laboratory Medicine, Affiliated Hospital of Nantong University, No. 20 Xisi Road, Nantong 226001, Jiangsu Province, China. mucunmeishan1130@qq.com
Key Words Biomarker; Circular RNA; Diagnosis; Gastric cancer; Plasma
Core Tip Circ_0004592 was significantly overexpressed in gastric cancer (GC) tissues and plasma. Reverse transcription and real-time fluorescent quantitative polymerase chain reaction was validated as a robust approach for the detection of circ_0004592. The expression level of circ_0004592 in the plasma of patients with precancerous lesions was increased relative to that in healthy controls, suggesting that plasma circ_0004592 may serve as an early diagnostic biomarker. Further, its levels in plasma decreased following surgical resection of gastric tumors. High circ_0004592 expression was associated with the histological type, depth of tumor invasion, and lymph node metastasis of GC. These observations highlight the potential of circ_0004592 as a valuable diagnostic and prognostic biomarker.
Publish Date 2024-06-15 02:49
Citation <p>Kong S, Xu YH, Zheng M, Ju SQ, Shi HC. Circ_0004592: An auxiliary diagnostic biomarker for gastric cancer. <i>World J Gastrointest Oncol</i> 2024; 16(6): 2757-2768</p>
URL https://www.wjgnet.com/1948-5204/full/v16/i6/2757.htm
DOI https://dx.doi.org/10.4251/wjgo.v16.i6.2757
Full Article (PDF) WJGO-16-2757-with-cover.pdf
Manuscript File 92561_Auto_Edited-YJP.docx
Answering Reviewers 92561-answering-reviewers.pdf
Audio Core Tip 92561-audio.mp3
Biostatistics Review Certificate 92561-biostatistics-statement.pdf
Conflict-of-Interest Disclosure Form 92561-conflict-of-interest-statement.pdf
Copyright License Agreement 92561-copyright-assignment.pdf
Approved Grant Application Form(s) or Funding Agency Copy of any Approval Document(s) 92561-foundation-statement.pdf
Institutional Review Board Approval Form or Document 92561-institutional-review-board-statement.pdf
Non-Native Speakers of English Editing Certificate 92561-non-native-speakers.pdf
Supplementary Material 92561-supplementary-material.pdf
Peer-review Report 92561-peer-reviews.pdf
Scientific Misconduct Check 92561-scientific-misconduct-check.png
Scientific Editor Work List 92561-scientific-editor-work-list.pdf
CrossCheck Report 92561-crosscheck-report.pdf