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Articles Published Processes
6/15/2024 2:49:03 AM | Browse: 223 | Download: 951
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Received |
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2024-01-29 17:10 |
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Peer-Review Started |
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2024-01-29 17:10 |
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First Decision by Editorial Office Director |
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2024-02-28 20:23 |
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Return for Revision |
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2024-02-28 20:23 |
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Revised |
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2024-03-12 13:20 |
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Publication Fee Transferred |
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Second Decision by Editor |
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2024-04-12 02:33 |
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Second Decision by Editor-in-Chief |
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Final Decision by Editorial Office Director |
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2024-04-12 05:34 |
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Articles in Press |
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2024-04-12 05:34 |
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Edit the Manuscript by Language Editor |
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Typeset the Manuscript |
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2024-05-14 12:41 |
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Publish the Manuscript Online |
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2024-06-15 02:49 |
| ISSN |
1948-5204 (online) |
| Open Access |
This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/ |
| Copyright |
©The Author(s) 2024. Published by Baishideng Publishing Group Inc. All rights reserved. |
| Article Reprints |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
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| Permissions |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
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| Publisher |
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
| Website |
http://www.wjgnet.com |
| Category |
Medical Laboratory Technology |
| Manuscript Type |
Basic Study |
| Article Title |
Circ_0004592: An auxiliary diagnostic biomarker for gastric cancer
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| Manuscript Source |
Unsolicited Manuscript |
| All Author List |
Shan Kong, Yan-Hua Xu, Ming Zheng, Shao-Qing Ju and Heng-Chuan Shi |
| ORCID |
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| Funding Agency and Grant Number |
| Funding Agency |
Grant Number |
| Jiangsu Province Laboratory Medical Research Special Fund Project |
No. SYH-3201160-0061(2023008) |
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| Corresponding Author |
Shao-Qing Ju, DPhil, Professor, Department of Laboratory Medicine, Affiliated Hospital of Nantong University, No. 20 Xisi Road, Nantong 226001, Jiangsu Province, China. mucunmeishan1130@qq.com |
| Key Words |
Biomarker; Circular RNA; Diagnosis; Gastric cancer; Plasma |
| Core Tip |
Circ_0004592 was significantly overexpressed in gastric cancer (GC) tissues and plasma. Reverse transcription and real-time fluorescent quantitative polymerase chain reaction was validated as a robust approach for the detection of circ_0004592. The expression level of circ_0004592 in the plasma of patients with precancerous lesions was increased relative to that in healthy controls, suggesting that plasma circ_0004592 may serve as an early diagnostic biomarker. Further, its levels in plasma decreased following surgical resection of gastric tumors. High circ_0004592 expression was associated with the histological type, depth of tumor invasion, and lymph node metastasis of GC. These observations highlight the potential of circ_0004592 as a valuable diagnostic and prognostic biomarker. |
| Publish Date |
2024-06-15 02:49 |
| Citation |
Kong S, Xu YH, Zheng M, Ju SQ, Shi HC. Circ_0004592: An auxiliary diagnostic biomarker for gastric cancer. World J Gastrointest Oncol 2024; 16(6): 2757-2768 |
| URL |
https://www.wjgnet.com/1948-5204/full/v16/i6/2757.htm |
| DOI |
https://dx.doi.org/10.4251/wjgo.v16.i6.2757 |
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