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Articles Published Processes
5/24/2024 8:33:43 AM | Browse: 254 | Download: 1026
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Received |
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2024-01-30 04:03 |
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Peer-Review Started |
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2024-01-30 04:03 |
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First Decision by Editorial Office Director |
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2024-02-07 06:16 |
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Return for Revision |
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2024-02-07 06:16 |
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Revised |
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2024-02-20 08:17 |
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Publication Fee Transferred |
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Second Decision by Editor |
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2024-03-21 02:51 |
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Second Decision by Editor-in-Chief |
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2024-03-24 05:47 |
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Final Decision by Editorial Office Director |
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2024-04-02 03:10 |
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Articles in Press |
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2024-04-02 03:10 |
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Edit the Manuscript by Language Editor |
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2024-04-06 22:59 |
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Typeset the Manuscript |
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2024-05-13 09:18 |
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Publish the Manuscript Online |
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2024-05-24 08:33 |
| ISSN |
1948-0210 (online) |
| Open Access |
This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/Licenses/by-nc/4.0/ |
| Copyright |
© The Author(s) 2024. Published by Baishideng Publishing Group Inc. All rights reserved. |
| Article Reprints |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
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| Permissions |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
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| Publisher |
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
| Website |
http://www.wjgnet.com |
| Category |
Pharmacology & Pharmacy |
| Manuscript Type |
Basic Study |
| Article Title |
Effect of ginsenoside Rg1 on hematopoietic stem cells in treating aplastic anemia in mice via MAPK pathway
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| Manuscript Source |
Unsolicited Manuscript |
| All Author List |
Jin-Bo Wang, Ming-Wei Du and Yan Zheng |
| ORCID |
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| Funding Agency and Grant Number |
| Funding Agency |
Grant Number |
| Hangzhou Municipal Bureau of Science and Technology |
2021WJCY366 |
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| Corresponding Author |
Yan Zheng, MMed, Staff Physician, Department of Hepatic, The Xixi Hospital of Hangzhou Affiliated to Zhejiang University of Traditional Chinese Medicine, No. 2 Hengbu Street, Liuliu Town, Xihu District, Hangzhou 310023, Zhejiang Province, China. zjhzzygood@163.com |
| Key Words |
Aplastic anemia; Ginsenoside Rg1; Myelosuppression; MAPK signaling pathway; Bone marrow; Hematopoietic stem cells |
| Core Tip |
This study evaluates ginsenoside Rg1’s efficacy in aplastic anemia (AA) treatment, focusing on its impact on bone marrow pathology, hematopoiesis, and inflammation in a cyclophosphamide-induced myelosuppression C57 mice model. It demonstrates that ginsenoside Rg1 not only reduces cell apoptosis and inflammation but also promotes hematopoietic recovery by inhibiting the MAPK signaling pathway, offering a potential therapeutic strategy for AA. |
| Publish Date |
2024-05-24 08:33 |
| Citation |
Wang JB, Du MW, Zheng Y. Effect of ginsenoside Rg1 on hematopoietic stem cells in treating aplastic anemia in mice via MAPK pathway. World J Stem Cells 2024; 16(5): 591-603
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| URL |
https://www.wjgnet.com/1948-0210/full/v16/i5/591.htm |
| DOI |
https://dx.doi.org/10.4252/wjsc.v16.i5.591 |
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