| ISSN |
1948-5182 (online) |
| Open Access |
This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/ |
| Copyright |
© The Author(s) 2024. Published by Baishideng Publishing Group Inc. All rights reserved. |
| Article Reprints |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
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| Permissions |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
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| Publisher |
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
| Website |
http://www.wjgnet.com |
| Category |
Gastroenterology & Hepatology |
| Manuscript Type |
Retrospective Cohort Study |
| Article Title |
Quantifying the natural growth rate of hepatocellular carcinoma: A real-world retrospective study in southwestern China
|
| Manuscript Source |
Unsolicited Manuscript |
| All Author List |
Li Tu, Hong Xie, Qi Li, Ping-Gui Lei, Pei-Ling Zhao, Fan Yang, Chi Gong, Yuan-Lin Yao and Shi Zhou |
| ORCID |
|
| Funding Agency and Grant Number |
| Funding Agency |
Grant Number |
| National Natural Science Foundation of China |
81960328 |
| Cultivate Project for the National Natural Science Foundation of China |
gyfynsfc[2020]-27 |
|
| Corresponding Author |
Hong Xie, Doctor, Professor, Clinical Medicine, Soochow University, No. 199 Renai Road, Suzhou 215123, Jiangsu Province, China. doctorxie2007@yeah.net |
| Key Words |
Hepatocellular carcinoma; Natural tumor growth pattern; Tumor volume doubling time; Tumor growth rate; Real-world retrospective study |
| Core Tip |
The present study offers real-world data, revealing a median tumor volume doubling time of 163 d for hepatocellular carcinoma (HCC) patients in Southwest China. These findings endorse the implementation of biannual surveillance and follow-up for this patient population. The observed heterogeneity in HCC growth, with approximately one-third of patients exhibiting indolent, intermediate, or rapid growth, highlights the necessity for individualized management and targeted treatment strategies based on specific tumor growth rate. Further research is essential to elucidate the mechanisms driving this growth heterogeneity and to inform clinical practice. |
| Publish Date |
2024-05-22 11:33 |
| Citation |
Tu L, Xie H, Li Q, Lei PG, Zhao PL, Yang F, Gong C, Yao YL, Zhou S. Quantifying the natural growth rate of hepatocellular carcinoma: A real-world retrospective study in southwestern China. World J Hepatol 2024; 16(5): 800-808 |
| URL |
https://www.wjgnet.com/1948-5182/full/v16/i5/800.htm |
| DOI |
https://dx.doi.org/10.4254/wjh.v16.i5.800 |
