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Articles Published Processes
5/11/2024 10:58:28 AM | Browse: 220 | Download: 903
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Received |
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2024-02-02 23:37 |
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Peer-Review Started |
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2024-02-02 23:37 |
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First Decision by Editorial Office Director |
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2024-02-29 20:07 |
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Return for Revision |
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2024-02-29 20:07 |
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Revised |
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2024-03-09 20:50 |
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Publication Fee Transferred |
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Second Decision by Editor |
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2024-04-17 02:30 |
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Second Decision by Editor-in-Chief |
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Final Decision by Editorial Office Director |
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2024-04-17 03:10 |
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Articles in Press |
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2024-04-17 03:10 |
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Edit the Manuscript by Language Editor |
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Typeset the Manuscript |
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2024-04-29 17:02 |
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Publish the Manuscript Online |
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2024-05-11 10:58 |
| ISSN |
1007-9327 (print) and 2219-2840 (online) |
| Open Access |
This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: Https://creativecommons.org/Licenses/by-nc/4.0/ |
| Copyright |
©The Author(s) 2024. Published by Baishideng Publishing Group Inc. All rights reserved. |
| Article Reprints |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
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| Permissions |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
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| Publisher |
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
| Website |
http://www.wjgnet.com |
| Category |
Gastroenterology & Hepatology |
| Manuscript Type |
Editorial |
| Article Title |
Angiotensin-converting enzyme 2 and AMPK/mTOR pathway in the treatment of liver fibrosis: Should we consider further implications?
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| Manuscript Source |
Invited Manuscript |
| All Author List |
Michele Barone |
| ORCID |
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| Funding Agency and Grant Number |
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| Corresponding Author |
Michele Barone, MD, PhD, Associate Professor, Section of Gastroenterology, Department of Precision and Regenerative Medicine - Jonian Area- University of Bari, Piazza G Cesare 11, Bari 70124, Italy. michele.barone@uniba.it |
| Key Words |
Renin-angiotensin system; Liver fibrosis; Hepatic stellate cells; Autophagy; Hepatocellular carcinoma |
| Core Tip |
In the light of clarifying the link between liver fibrosis and the development of hepatocellular carcinoma, we discussed the renin-angiotensin system involvement in liver fibrosis and hepatocarcinoma development, the specific mechanisms by which angiotensin-converting enzyme 2 (ACE2) regulates hepatic stellate cell (HSC) autophagy and consequently fibrosis, and the ACE2-dependent upstream signals modulating the AMP-activated protein kinase/mammalian target of the rapamycin pathway implicated in the regulation of HSC activation. |
| Publish Date |
2024-05-11 10:58 |
| Citation |
Barone M. Angiotensin-converting enzyme 2 and AMPK/mTOR pathway in the treatment of liver fibrosis: Should we consider further implications? World J Gastroenterol 2024; 30(18): 2391-2396 |
| URL |
https://www.wjgnet.com/1007-9327/full/v30/i18/2391.htm |
| DOI |
https://dx.doi.org/10.3748/wjg.v30.i18.2391 |
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