Publication Name	World Journal of Gastroenterology
Manuscript ID	92715
Country	China

Received	2024-02-03 17:34
Peer-Review Started	2024-02-03 17:34
To Make the First Decision
Return for Revision	2024-02-29 20:04
Revised	2024-03-09 14:15
Second Decision	2024-04-24 02:47
Accepted by Journal Editor-in-Chief
Accepted by Executive Editor-in-Chief	2024-04-24 05:11
Articles in Press	2024-04-24 05:11
Publication Fee Transferred
Edit the Manuscript by Language Editor
Typeset the Manuscript	2024-05-09 07:53
Publish the Manuscript Online	2024-05-20 09:15

ISSN	1007-9327 (print) and 2219-2840 (online)
Open Access	This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/
Copyright	© The Author(s) 2024. Published by Baishideng Publishing Group Inc. All rights reserved.
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Website	http://www.wjgnet.com

Category	Cell Biology
Manuscript Type	Basic Study
Article Title	Novel lactylation-related signature to predict prognosis for pancreatic adenocarcinoma
Manuscript Source	Unsolicited Manuscript
All Author List	Tian Peng, Fang Sun, Jia-Chun Yang, Mei-Hong Cai, Man-Xiu Huai, Jia-Xing Pan, Fei-Yu Zhang and Lei-Ming Xu
ORCID	Author(s) ORCID Number Fang Sun http://orcid.org/0000-0002-6688-4676 Man-Xiu Huai http://orcid.org/0000-0002-3283-4152 Jia-Xing Pan http://orcid.org/0009-0005-1318-6320 Fei-Yu Zhang http://orcid.org/0009-0005-7203-6322 Lei-Ming Xu http://orcid.org/0000-0002-6735-4853
Funding Agency and Grant Number	Funding Agency Grant Number National Natural Science Foundation of China 82172737 Shanghai Science and Technology Development Funds (Shanghai Sailing Program) 22YF1427600
Corresponding Author	Lei-Ming Xu, MD, PhD, Chief Doctor, Professor, Department of Gastroenterology, Xinhua Hospital Affiliated to Shanghai Jiao Tong University, No. 1665 Kongjiang Road, Shanghai 200092, China. xuleiming@xinhuamed.com.cn
Key Words	Pancreatic adenocarcinoma; Lactylation; Prognosis; Immunotherapy; Tumor microenvironment
Core Tip	Our article presents the first study on lactylation modification in pancreatic cancer, establishing a lactylation-related signature that offers new strategic directions for tumor prognosis prediction and combination antitumor immunotherapy. It employs an innovative approach, combining both dry lab and wet lab experimental methods, to validate the genes most closely associated with lactylation.
Publish Date	2024-05-20 09:15
Citation	<p>Peng T, Sun F, Yang JC, Cai MH, Huai MX, Pan JX, Zhang FY, Xu LM. Novel lactylation-related signature to predict prognosis for pancreatic adenocarcinoma. <i>World J Gastroenterol</i> 2024; 30(19): 2575-2602</p>
URL	https://www.wjgnet.com/1007-9327/full/v30/i19/2575.htm
DOI	https://dx.doi.org/10.3748/wjg.v30.i19.2575

Full Article (PDF)	WJG-30-2575-with-cover.pdf
The ARRIVE Guidelines	92715-The ARRIVE guidelines.pdf
Manuscript File	92715_Auto_Edited-YJP.docx
Answering Reviewers	92715-Answering reviewers.pdf
Audio Core Tip	92715-Audio core tip.mp3
Biostatistics Review Certificate	92715-Biostatistics statement.pdf
Conflict-of-Interest Disclosure Form	92715-Conflict-of-interest statement.pdf
Copyright License Agreement	92715-Copyright license agreement.pdf
Approved Grant Application Form(s) or Funding Agency Copy of any Approval Document(s)	92715-Grant application form(s).pdf
Institutional Animal Care and Use Committee Approval Form or Document	92715-Institutional animal care and use committee statement.pdf
Non-Native Speakers of English Editing Certificate	92715-Language certificate.pdf
Supplementary Material	92715-Supplementary material.pdf
Peer-review Report	92715-Peer-review(s).pdf
Scientific Misconduct Check	92715-Bing-Li L-2.png
Scientific Editor Work List	92715-Scientific editor work list.pdf
CrossCheck Report	92715-CrossCheck.png
CrossCheck Report	92715-CrossCheck report.pdf